chelerythrine


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chelerythrine

a toxic alkaloid found in the plant chelidonium majus.
References in periodicals archive ?
Over the last years, studies on sanguinarine (1) and chelerythrine (2) have focused also on their potential as anti-cancer drugs.
Sanguinarine (1) and chelerythrine (2) were isolated in authors' laboratory by preparative column chromatography (Dostal et al.
Two hours after LPS stimulation, cells influenced by sanguinarine (1) and chelerythrine (2) significantly declined the CCL-2 expression by a factors of 3.
Chelerythrine (2) increased the level of IL-1RA mRNA only by a factor of 1.
Sanguinarine (1) and chelerythrine (2) are biologically active substances in preparations used in the treatment of dental plaque formation and inflammatory periodontal diseases, but the mechanism of anti-inflammatory activity of these alkaloids is still not known in details.
Cytotoxicity assay showed that cytotoxic effect of sanguinarine (1) was much higher than that of chelerythrine (2) in THP-1 cells and both alkaloids inhibited viability in dose-dependent manner, which is consistent with other studies (Malikova et at.
1]H-NMR resonances of alkaloids like chelidonine, protopine, coptisine, sanguinarine, chelerythrine and berberine are expected in the range of 7.
A more detailed characterization of the different Chelidonii herba extracts was done by quantifying chelidonine, protopine, sanguinarine, coptisine, chelerythrine and berberine of the Chelidonii herba extracts by RP-HPLC (Fig.
Investigation of sanguinarine and chelerythrine effects on CYP1A1 expression and activity in human hepatoma cells.