chelate (redirected from chelators)

chelate /che·late/ (ke´lāt)

1. to combine with a metal in complexes in which the metal is part of a ring.

2. by extension, a chemical compound in which a metallic ion is sequestered and firmly bound into a ring within the chelating molecules. Chelates are used in chemotherapy of metal poisoning.

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che·late (klt)

n.

A chemical compound in the form of a heterocyclic ring, containing a metal ion attached by coordinate bonds to at least two nonmetal ions.

v.

1. To combine a metal ion with a chemical compound to form a ring.

2. To remove a heavy metal, such as lead or mercury, from the bloodstream by means of a chelate.

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chelate adj.

che·lation n.

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Chelate

A chemical that binds to heavy metals in the blood, thereby helping the body to excrete them in urine.

Mentioned in: Nephrotoxic Injury

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chelate

[kē′lāt]

Etymology: Gk, chele, claw

1  v, to form a bond, thus creating a ringlike complex. An example is the interaction of a metal ion and two or more polar groups of a single molecule.

2  n, (in medicine) any coordination compound composed of a central metal ion and an organic molecule with multiple bonds arranged in ring formations, used especially in chemotherapeutic treatments for metal poisoning.

3  adj, pertaining to chelation.

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chelate

to combine with a metal in complexes in which the metal is part of a ring; by extension, a chemical compound in which a metallic ion is sequestered and firmly bound into a ring within the chelating molecule. Chelates are used in treatment of metal poisoning.