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Chelate
(redirected from chelator)

   Also found in: Dictionary/thesaurus, Encyclopedia, Wikipedia, Hutchinson 0.04 sec.
chelate /che·late/ (ke´lat)
1. to combine with a metal in complexes in which the metal is part of a ring.
2. by extension, a chemical compound in which a metallic ion is sequestered and firmly bound into a ring within the chelating molecules. Chelates are used in chemotherapy of metal poisoning.

che·late (klt)
n.
A chemical compound in the form of a heterocyclic ring, containing a metal ion attached by coordinate bonds to at least two nonmetal ions.
v.
1. To combine a metal ion with a chemical compound to form a ring.
2. To remove a heavy metal, such as lead or mercury, from the bloodstream by means of a chelate.

chelate adj.
che·lation n.

Chelate
A chemical that binds to heavy metals in the blood, thereby helping the body to excrete them in urine.
Mentioned in: Nephrotoxic Injury

chelate
to combine with a metal in complexes in which the metal is part of a ring; by extension, a chemical compound in which a metallic ion is sequestered and firmly bound into a ring within the chelating molecule. Chelates are used in treatment of metal poisoning.

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In all cases, several cycles of chelator administration given over a period of months are required to produce an adequate and durable reduction of Pb in blood.
Our final step is to use transdermal DMPS, a chelator that can be applied to the skin.
We want chelators that are specific for our [radioactive] metals of interest" but that don't bind to others, such as calcium, which is a major ingredient of concrete and marble, says Mark E.
 
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