chelate

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Related to chelations: Chelant

chelate

 [ke´lāt]
1. to combine with a metal in complexes in which the metal is part of a ring.
2. by extension, a chemical compound in which a metallic ion is sequestered and firmly bound into a ring within the chelating molecule. Chelates are used in chemotherapy of metal poisoning.

che·late

(kē'lāt),
1. To effect chelation.
2. Pertaining to chelation.
3. A complex formed through chelation.

chelate

/che·late/ (ke´lāt)
1. to combine with a metal in complexes in which the metal is part of a ring.
2. by extension, a chemical compound in which a metallic ion is sequestered and firmly bound into a ring within the chelating molecules. Chelates are used in chemotherapy of metal poisoning.

chelate

(kē′lāt′)
adj. Zoology
Having chelae or resembling a chela.
n. Chemistry
A chemical compound in the form of a heterocyclic ring, containing a metal ion attached by coordinate bonds to at least two nonmetal ions.
tr.v. che·lated, che·lating, che·lates
1. Chemistry To combine (a metal ion) with a chemical compound to form a ring.
2. Medicine To remove (a heavy metal, such as lead or mercury) from the bloodstream by means of a chelate, such as EDTA.

che′lat·a·ble adj.
che·la′tion n.
che′la′tor n.

chelate

[kē′lāt]
Etymology: Gk, chele, claw
1 v, to form a bond, thus creating a ringlike complex. An example is the interaction of a metal ion and two or more polar groups of a single molecule.
2 n, (in medicine) any coordination compound composed of a central metal ion and an organic molecule with multiple bonds arranged in ring formations, used especially in chemotherapeutic treatments for metal poisoning.
3 adj, pertaining to chelation.

che·late

(kē'lāt)
1. To effect chelation.
2. Pertaining to chelation.
3. A complex formed through chelation.

chelate

  1. possessing claws or pincer-like appendages.
  2. to combine with a metal ion to form a stable compound.

Chelate

A chemical that binds to heavy metals in the blood, thereby helping the body to excrete them in urine.
Mentioned in: Nephrotoxic Injury

chelate

to combine with a metal in complexes in which the metal is part of a ring; by extension, a chemical compound in which a metallic ion is sequestered and firmly bound into a ring within the chelating molecule. Chelates are used in treatment of metal poisoning.
References in periodicals archive ?
So they made up their minds long ago that it was crazy to study chelation therapy.
when you implied that there's some avenue for chelation therapy as a part of the complement of medications or stuff, I kept thinking that it would end up being a patented agent, made into a drug.
You know, the receiving IV chelation is such a daunting treatment for patients, that it's the--the ideal would be if a pharmaceutical company develops an oral version of this that they can make some money on so that they will do the research, and that it would be yet another pill that post-heart-attack patients would take or diabetics would take.
That you're able to call your chelation coinvestigators colleagues
If all the economic--and this is why I'm actually happy, even though it might make my chelation colleagues upset, that it doesn't get covered by insurance.
has this chelation trial changed anything in the way you approach your own cardiovascular prevention?
Improved myocardial perfusion in patients with advance ischemic heart disease with an integrative management program including EDTA chelation therapy.
A nonsurgical approach to obstructive carotid stenosis using EDTA chelation.
Effect of EDTA chelation and supportive multivitamin/trace mineral supplementation of chronic lung disorders: a study of FVC and FEV.
Visual field evidence of macular degeneration reversal using a combination of EDTA chelation and multiple vitamin and trace mineral therapy.
Benefits of EDTA chelation therapy in arteriosclerosis: a retrospective study of 470 patients.
EDTA chelation therapy in chronic degenerative disease.