chelate /che·late/ (ke´lāt)
Chelate
chelate
1. to combine with a metal in complexes in which the metal is part of a ring.
2. by extension, a chemical compound in which a metallic ion is sequestered and firmly bound into a ring within the chelating molecules. Chelates are used in chemotherapy of metal poisoning.
che·late (k  l t )n. A chemical compound in the form of a heterocyclic ring, containing a metal ion attached by coordinate bonds to at least two nonmetal ions. v. 1. To combine a metal ion with a chemical compound to form a ring. 2. To remove a heavy metal, such as lead or mercury, from the bloodstream by means of a chelate. che late adj.che·la tion n. |
Chelate
A chemical that binds to heavy metals in the blood, thereby helping the body to excrete them in urine.
Mentioned in: Nephrotoxic Injury
chelate
[kē′lāt]
Etymology: Gk, chele, claw
1 v, to form a bond, thus creating a ringlike complex. An example is the interaction of a metal ion and two or more polar groups of a single molecule.
2 n, (in medicine) any coordination compound composed of a central metal ion and an organic molecule with multiple bonds arranged in ring formations, used especially in chemotherapeutic treatments for metal poisoning.
3 adj, pertaining to chelation.
chelate
to combine with a metal in complexes in which the metal is part of a ring; by extension, a chemical compound in which a metallic ion is sequestered and firmly bound into a ring within the chelating molecule. Chelates are used in treatment of metal poisoning.
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