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chelate |
Also found in: Dictionary/thesaurus, Encyclopedia, Hutchinson | 0.03 sec. |
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chelate /che·late/ (ke´lāt) 1. to combine with a metal in complexes in which the metal is part of a ring. 2. by extension, a chemical compound in which a metallic ion is sequestered and firmly bound into a ring within the chelating molecules. Chelates are used in chemotherapy of metal poisoning.
Chelate A chemical that binds to heavy metals in the blood, thereby helping the body to excrete them in urine. Mentioned in: Nephrotoxic Injury chelate [kē′lāt] Etymology: Gk, chele, claw 1 v, to form a bond, thus creating a ringlike complex. An example is the interaction of a metal ion and two or more polar groups of a single molecule. 2 n, (in medicine) any coordination compound composed of a central metal ion and an organic molecule with multiple bonds arranged in ring formations, used especially in chemotherapeutic treatments for metal poisoning. 3 adj, pertaining to chelation. chelate to combine with a metal in complexes in which the metal is part of a ring; by extension, a chemical compound in which a metallic ion is sequestered and firmly bound into a ring within the chelating molecule. Chelates are used in treatment of metal poisoning. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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Neurobehavioral function and tibial and chelatable lead levels in 543 former organolead workers. A 4-hr urine collection after oral administration of 10 mg/kg dimercaptosuccinic acid (DMSA) was also obtained to measure DMSA chelatable lead and creatinine clearance (787 participants completed this collection). The estimated concentration of iron bound to the LMW ligands (the so-called chelatable iron) is 1-10 [micro]M in rodent and human cells (Petrat et al. |
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