chaperonopathies

chaperonopathies

Structural abnormalities of CHAPERONES resulting from genetic mutations or from later factors such as amino acid oxidation, deamination, glycation, phosphorylation, acetylation, nitrosylation or trucation of the protein molecule. Also known as ‘sick chaperones’.
References in periodicals archive ?
Wide perspectives on aging are covered, ranging from metabolic and cellular interventions in aging, oxidative stress resistance, protein folding and quality control, as well as the troublesome relationship between prevention of chaperonopathies and the risk for cancer.