chaperone


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chap·e·rone

(shap-ĕ-rōn),
1. A protein required for the proper folding and/or assembly of another protein or protein complex.
2. One who accompanies a physician during physical examination of a patient of the opposite gender (from the physician).
[Eng. escort, protector, fr. Fr. chaperon, hood, fr. chape, cape, fr. L.L. cappa, fr. L. caput, head]

chaperone

/chap·er·one/ (shap´er-ōn) someone or something that accompanies and oversees another.
molecular chaperone  any of a diverse group of proteins that oversee the correct intracellular folding and assembly of polypeptides without being components of the final structure.

chaperone

or

chaperon

(shăp′ə-rōn′)
n.
Any of a diverse group of proteins that assist macromolecules, such as proteins and nucleic acids, to assemble and fold into the proper three-dimensional structure as they are being synthesized. Also called molecular chaperone.

chap′er·on′age (-rō′nĭj) n.

chaperone

Cell biology
Any of a class of cytoplasmic proteins found in both prokaryotes and eukaryotes, which facilitate the correct assembly or disassembly of newly synthesised oligomeric protein complexes, participating in transmembrane targeting and protein folding.

Medspeak-UK
A person, generally employed by a medical doctor or (NHS) hospital trust, who stays with the patient while the doctor is examining a patient or performing a procedure.
 
Vox populi
A person who accompanies a child or adolescent under the age of majority (adulthood) during an event such as a date or a school dance.

chap·e·rone

(shap'ĕ-rōn)
1. A protein required for the proper folding and/or assembly of another protein or protein complex.
2. One who accompanies a physician during physical examination of a patient of the opposite gender (from that of the physician).
[Eng. escort, protector, fr. Fr. chaperon, hood, fr. chape, cape, fr. L.L. cappa, fr. L. caput, head]

chaperone

a PROTEIN MOLECULE which can assist in the folding, assembly or transport of other proteins in a CELL.

chaperone

a family of proteins that aid in the folding of target proteins.
References in periodicals archive ?
Room-scale VR still isn't a perfect experience; you inevitably find yourself wanting a real open-world environment, and, inevitably, end up triggering Chaperone - or reaching the limits of the system's wires - before you go too far.
The report found he was able to manipulate the policies on chaperones by befriending patients and families.
They've said it's fine for us chaperone the children.
37) DGJ showed the chaperone effect specifically on mutant [alpha]-galactosidase A.
Small Heat Shock Proteins (sHSP): Structure and Chaperone Function_
The Drowsy Chaperone begins when, to chase his blues away, a modern day musical theatre addict known simply as 'Man in Chair' drops the needle on his favorite LP — the 1928 musical comedy The Drowsy Chaperone.
In the incident of February last year he admits failing to use a consulting room for the examination, carrying out the procedure while the patient was stood up and without offering a chaperone.
These dances are for students in grades 5, 6, 7, and 8 only and there are several adult chaperones to ensure everyone's safety.
So, what is an intimate examination, what is a chaperone, and what are the implications of chaperones being present during these examinations?
Topics addressed in the 14 included presentations are the history of the understanding of cell stress; systems biology of molecular chaperone networks; unusual cellular disposition of the mitochondrial chaperones Hsp60, Hsp70, and Hsp10; cell surface molecular chaperones as endogenous modulators of innate immune response; cell stress proteins in extracellular fluids; Hsp60 and the immune system; novel immunotherapies from cell stress proteins; cell stress proteins as modulators of bacteria-host interactions; chaperonin 60 and microphage activation; extracellular functions of thioredoxin; Hsp27 as an anti-inflammatory and immunomodulatory stress protein acting to dampen immune function; and binding immunoglobulin protein as a potential new therapy for the treatment of rheumatoid arthritis.
On goes the record, and out come the "Chaperone" players spilling into Man's apartment: Janet the stage star (played by Andrea Chamberlain), set to marry a man (Mark Ledbetter) she met on a ship; the producer (Cliff Bemis) who would rather she didn't; George (Richard Vida), the groom's tap-happy best man; the buffoonish Latin lover, Adolpho (James Moye), dispatched to ruin the nuptials; a pair of gangsters (Paul and Peter Riopelle) posing as bakery chefs; and Janet's chaperone (Nancy Opel), who never met a martini she didn't like.
A chaperone protein (bottom, yellow) called SecB guides the folding of another protein (transparent) in this artist's illustration.