In calculus from a young adult, they discovered the presence of compounds (dihydroazulene, chamazulene
and methylherniarin) that occur in yarrow (Achillea millefolium) and camomile (Matriarca chamomilla).
chamomilla EO, chamazulene
and [alpha]-bisabolol was established by in vitro and in vivo experiments.
The essence (including: farnesene, chamazulene
, bisabolol, oxide of A & B).
The main constituents found in the essential oils of the studied Asteraceae species were bisabolol oxide A, bisabolone oxide A, (Z)-en-yne-dicycloether, bisabolol oxide B, [alpha]-bisabolol, and chamazulene
in the essential oil of Chamomilla recutita; (Z)-en-yne-dicycloether, geranyl isovalerate, and (E)-[beta]-farnesene in C.
Books on herbal remedies tout the substance chamazulene
- especially strong in the flowers of the attractive 2-foot-tall chamomile shrub - as treatment for a variety of illnesses that range from menstrual cramps, indigestion and intestinal gas to allergies, eczema and an anti-infectant for cuts and scrapes.
36-38) Complementing the action of this highly bioactive compound are other constituents such as bisabolol and chamazulene
which also contribute to chamomile's potent anti-inflammatory capacity.
absinthium has been the object of several studies [1-12], especially for its contents of such compounds as thujone isomers and chamazulene
with pharmacodynamic properties.
A number of constituents of chamomile may have an effect including chamazulene
with anti-inflammatory and antioxidant effects; apigenin with anti-inflammatory, analgesic and antineoplastic effects; flavonoids with anti-inflammatory and anxiolytic activity; and alpha-bisabolol with anti inflammatory and digestive effects.
The principal components of the essential oil extracted from the flowers are the terpenoids a-bisabolol and its oxides and azulenes, including chamazulene
, whereas the main constituents of the extracts prepared from the flowers include several phenolic compounds primarily the flavonoids apigenin, quercetin, patuletin, luteolin and their glucosides (Franke and Schilcher 2005; McKay and Blumberg 2006).
The results showed that, highest number of flower per plant, fresh flower per plant, dried flower per plant, fresh flower yield, dried flower yield, essential oil yield, chamazulene
percentage and chamazulene
yield were obtained by the first planting time (5 March).
The biologically active substances in chamomile essential oil are [alpha]-bisabolol, bisabolol oxides, chamazulene
, and enyn-dicycloethers [1-5].
Camphor, davanone, bornyl acetate, 4-terpineol and chamazulene
were, however, reported to be major compounds of essential oil of the plant (Burits et al.