chalone


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chalone

 [kal´ōn]
a group of tissue-specific, water-soluble substances that are produced within a tissue and that inhibit mitosis of the cells of that tissue and whose action is reversible.

cha·lone

(kā'lōn),
Originally, a hormone (for example, enterogastrone) that inhibits rather than stimulates; now, mitotic inhibitor (often glycoproteins) elaborated by a tissue and active only on that type of tissue, regardless of species; thus, a reversible tissue-specific mitotic inhibitor.
[G. + chalaō, to relax, + -one]

chalone

/chal·one/ (kal´ōn) a group of tissue-specific water-soluble substances that are produced within a tissue and that inhibit mitosis of cells of that tissue and whose action is reversible.

chalone

(kā′lōn′, kăl′ōn′)
n.
Any of several polypeptides that cause the reversible inhibition of mitosis in the cells that secrete them.

chalone

[kā′lōn]
Etymology: Gk, chalan, to relax
any one of numerous polypeptide inhibitors that are elaborated by a tissue and function like hormones on specific target organs.

cha·lone

(kal'ōn)
Any of a number of mitotic inhibitors elaborated by a tissue and active only on that type of tissue, regardless of species; a reversible tissue-specific mitotic inhibitor.
[G. + chalaō, to relax, + -one]

chalone

one of a group of chemicals (PEPTIDES and GLYCOPROTEINS) occurring in living animal tissues which specifically inhibit MITOSIS.

chalone

a group of tissue-specific, water-soluble substances that are produced within a tissue and that inhibit mitosis of the cells of that tissue and whose action is reversible.
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References in periodicals archive ?
Chalone and its directors, executive officers, certain members of management and certain employees may be deemed to be participants in the solicitation of proxies in connection with the proposed merger.
In the year to December 31, 2003, Chalone reported gross revenues of $69.
Brands include: Beaulieu Vineyard, Sterling Vineyards, Sterling Vintner's Collection, Rosenblum Cellars, Chalone Vineyard, Acacia Vineyard, and Provenance Vineyards.
4 miles), or follow the more gradual (but still steep) descent along High Peaks Trail to Chalone Creek; then take the Bear Gulch Trail back to Moses Spring (6.
Easiest is Old Pinnacles, running streamside from the Chalone picnic area along Chalone Creek to the Balconies cliffs.
The company produces and markets Beaulieu Vineyard, Sterling Vineyards, Sterling Vintner's Collection, the wines of the Chalone Wine Group, Solaris, Archetype, Vinavera and Blossom Hill, as well as the French wines of Barton & Guestier.
19, 2013 /PRNewswire/ -- Chalone Vineyard announces the first commercial release in more than a decade of its popular Gavilan wine brand.
Also chenin blanc and pinot blanc 2004s ($22 each) from Chalone Vineyard, probably Monterey County's most prestigious winery, are on the shelves.
John Probst, a veteran of 15 years in the Washington State wine industry; is the new general manager of Sagelands Vineyard, announced Chalone Wine Group.
Diageo Chateau & Estate Wines produces and markets Beaulieu Vineyard, Sterling Vineyards, the wines of The Chalone Wine Group, Sterling Vintner's Collection, Solaris, Vinavera, Archetype and Blossom Hill, as well as the French wines of Barton & Guestier.
Today, the winery works closely with top winegrowers in the Santa Lucia Highlands, Santa Rita Hills, Arroyo Grande Valley, Santa Maria Valley, Russian River Valley, and Chalone appellations.
The Californians picked for the tasting were Chalone, Kendall-Jackson, Justin, Ojai and Ravenswood.