challenge

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challenge

 [chal´enj]
1. to administer a chemical substance to a patient for observation of whether the normal physiological response occurs.
2. in immunology, to administer antigen to evoke an immunologic response in a previously sensitized individual.
3. the administration of such a substance in order to assess for a response; called also provocation.
bronchial challenge (inhalational challenge) bronchial challenge test.

challenge

/chal·lenge/ (chal´enj)
1. to administer a substance to monitor for the normal physiological response.
2. in immunology, to administer an antigen to monitor the response in a sensitized person.

challenge

(chăl′ənj)
n.
Immunology The induction or evaluation of an immune response in an organism by administration of a specific antigen to which it has been sensitized.
v. chal·lenged, chal·lenging, chal·lenges
v.tr.
Immunology To induce or evaluate an immune response in (an organism) by administering a specific antigen to which it has been sensitized.

chal′lenge·a·ble adj.

challenge

1 a method of testing the sensitivity of an individual to a hormone, allergen, or other substance by administering a sample. A small amount may be injected to determine whether the immune system will react by producing appropriate antibodies.
2 a term used to describe the rapid or concentrated infusion of a substance such as potassium or magnesium in the face of a life-threatening deficiency or a rapid infusion of IV fluid to differentiate between fluid deficit or renal failure as the cause of severely decreased urine output.

challenge

Immunology The administration of an antigen or allergen to a person who has been previously exposed to the antigen, specifically to evoke an immune response

challenge,

n a stimulating or de-manding circumstance. To develop effective problem-solving skills and strategies, it is necessary to perceive such circumstance as inconvenience or burden instead of overwhelming impediments.
References in periodicals archive ?
Finally and most challengingly, it must be recognised that the fundamental issue underlying the migration of health professionals from poor to better-off regions and countries, of inequitable access to health care, and of inequitable health outcomes, is the vast and unjustifiable difference in wealth between the few rich and the many poor countries.
Alternately, you can challengingly practice a new behavior and, based on the results, find how your assumptions can change.
40) He continues, "The 1662 Burial Service begins with one of the most challengingly hopeful assertions in the world.
His memorial, unswept and otherwise obscure, is nonetheless restored to its Lacanian nonreligious beauty, and the mystery of the dead apothecary challengingly set alongside the equivocations of Shakespeare's celebrated Sonnet 55, which also claims immortality for its addressee.
Even by Scandinavian standards, the Svalbard archipelago is challengingly remote.
With the New World Square proposals unlikely to win universal acclaim, apart from aesthetic considerations, any design for this site should be critically examined as to how it might complement the eventual provision of a cruise liner facility, protect the view of the Three Graces from the river and, more challengingly, the historic riverside vista of the parish church.
Rather than looking at congregants and deciding what they don't want, we should teach them Torah, lovingly and challengingly.
While Pierre sets about through Le Confessionnal to discover the truth, Francois has to come to terms with the elusive nature of truth itself--most challengingly manifested in the fact that Francois is increasingly unsure of whether or not he actually in Marie-Claire's murderer.
You were going to straighten me out, "Jay said challengingly.
FOR ALMOST A CENTURY AND A HALF GEORGE MEREDITH'S MODERN LOVE HAS been recognized as a challengingly, troublingly modern poem.
With women also making challengingly political documentaries like On the Right Track Cheolroh(Wi Eui Saram Deul dir.
Her characterisation of unregenerate women challengingly relies upon existing stereotypes of disobedient or sinful women.