challenge

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challenge

 [chal´enj]
1. to administer a chemical substance to a patient for observation of whether the normal physiological response occurs.
2. in immunology, to administer antigen to evoke an immunologic response in a previously sensitized individual.
3. the administration of such a substance in order to assess for a response; called also provocation.
bronchial challenge (inhalational challenge) bronchial challenge test.

challenge

/chal·lenge/ (chal´enj)
1. to administer a substance to monitor for the normal physiological response.
2. in immunology, to administer an antigen to monitor the response in a sensitized person.

challenge

(chăl′ənj)
n.
Immunology The induction or evaluation of an immune response in an organism by administration of a specific antigen to which it has been sensitized.
v. chal·lenged, chal·lenging, chal·lenges
v.tr.
Immunology To induce or evaluate an immune response in (an organism) by administering a specific antigen to which it has been sensitized.

chal′lenge·a·ble adj.

challenge

1 a method of testing the sensitivity of an individual to a hormone, allergen, or other substance by administering a sample. A small amount may be injected to determine whether the immune system will react by producing appropriate antibodies.
2 a term used to describe the rapid or concentrated infusion of a substance such as potassium or magnesium in the face of a life-threatening deficiency or a rapid infusion of IV fluid to differentiate between fluid deficit or renal failure as the cause of severely decreased urine output.

challenge

Immunology The administration of an antigen or allergen to a person who has been previously exposed to the antigen, specifically to evoke an immune response

challenge,

n a stimulating or de-manding circumstance. To develop effective problem-solving skills and strategies, it is necessary to perceive such circumstance as inconvenience or burden instead of overwhelming impediments.
References in periodicals archive ?
Similar reductions in the number of severe challenging behaviors were obtained in Classroom B following the implementation of the strategy.
The majority of the severe challenging behaviors exhibited by children were aggressive in nature.
The severe challenging behaviors exhibited by children with EBD imperil their academic, social, and vocational survival (Kazdin, 1987).
First, on average, the strategy appeared to result in substantial decreases in the number of severe challenging behaviors exhibited by children with EBD.
First, a large number of severe challenging behaviors exhibited by children with EBD may be averted with the application of a universal strategy.
3 Bearing Witness: Challenging Behaviour and its Contribution to Trauma and Vicarious Trauma.
The Diagnosis of Deaf People with Challenging Behaviour.
Neuropsychological, Behavioural and Linguistic Factors in Challenging Behaviour in Deaf People.
Psychodynamic Approaches to Understanding Challenging Behaviour.
Autistic Spectrum Disorder, Deafness and Challenging Behaviour.
Newdow has filed a new lawsuit once again challenging the Pledge and the ACLJ will once again file briefs opposing that challenge.