challenge

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challenge

 [chal´enj]
1. to administer a chemical substance to a patient for observation of whether the normal physiological response occurs.
2. in immunology, to administer antigen to evoke an immunologic response in a previously sensitized individual.
3. the administration of such a substance in order to assess for a response; called also provocation.
bronchial challenge (inhalational challenge) bronchial challenge test.

challenge

/chal·lenge/ (chal´enj)
1. to administer a substance to monitor for the normal physiological response.
2. in immunology, to administer an antigen to monitor the response in a sensitized person.

challenge

(chăl′ənj)
n.
Immunology The induction or evaluation of an immune response in an organism by administration of a specific antigen to which it has been sensitized.
v. chal·lenged, chal·lenging, chal·lenges
v.tr.
Immunology To induce or evaluate an immune response in (an organism) by administering a specific antigen to which it has been sensitized.

chal′lenge·a·ble adj.

challenge

1 a method of testing the sensitivity of an individual to a hormone, allergen, or other substance by administering a sample. A small amount may be injected to determine whether the immune system will react by producing appropriate antibodies.
2 a term used to describe the rapid or concentrated infusion of a substance such as potassium or magnesium in the face of a life-threatening deficiency or a rapid infusion of IV fluid to differentiate between fluid deficit or renal failure as the cause of severely decreased urine output.

challenge

Immunology The administration of an antigen or allergen to a person who has been previously exposed to the antigen, specifically to evoke an immune response

challenge,

n a stimulating or de-manding circumstance. To develop effective problem-solving skills and strategies, it is necessary to perceive such circumstance as inconvenience or burden instead of overwhelming impediments.
References in periodicals archive ?
The challenge to departments at the federal level was broader and more ambitious.
Only one person from the team is required to complete a trick or challenge to earn the points (unless the challenge specifically says "everyone.
8 percent in 2004-creating a challenge of overwhelming proportions.
As new technology enters the industry, it also becomes part of the Challenge.
In addition to describing the various challenges offered by classroom teachers, I will describe some possible resolutions to these challenges in the hope that teachers will find ways to implement a workshop approach to reading instruction during these troubling times.
We bring a robust tool kit to the challenges of preserving international order.
But if somebody said 10 or 20 years ago that we were going to challenge the Pledge of Allegiance or this tiny little cross on the county seal, the argument would have been that was far-fetched too.
To use the price challenge form in LIDB, you must have a 128-bit encryption enabled browser such as Netscape Communicator or Internet Explorer v.
And some, the Reporter found, are not prepared to defend themselves against such challenges, or savvy enough to launch them.
You would not have come this far had you not been up to the challenges before you.
Basing their performance on the honor system truly challenges those students who have less than stellar physical abilities.