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cetirizine

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cetirizine /ce·ti·ri·zine/ (sĕ-tir´ĭ-zēn) a nonsedating antihistamine used as the hydrochloride salt in the treatment of allergic rhinitis, chronic idiopathic urticaria, and asthma.
cetirizine,
an H1-histamine antagonist.
indications It is used to treat allergy symptoms and rhinitis.
contraindications Known hypersensitivity to this drug, lactation, and severe hepatic disease prohibit its use. It also should not be used in newborns or premature infants.
adverse effects Life-threatening effects include hemolytic anemia, thrombocytopenia, leukopenia, agranulocytosis, pancytopenia, and dysrhythmias (rare). Other serious adverse effects include urinary retention, impotence, diarrhea, vomiting, sedation, confusion, blurred vision, tremors, hypotension, palpitations, bradycardia, and tachycardia. Common side effects are thickening of bronchial secretions, nausea, drowsiness, and headache.

cetirizine [sĕ-tir´ĭ-zēn]
a nonsedating antihistamine administered orally in the form of the hydrochloride salt for treatment of allergic rhinitis and chronic hives, and as a treatment adjunct for asthma.

antihistamine 
Any substance that reduces the effect of histamine or blocks histamine receptors, usually the histamine 1 (H1) receptor. It is used in the treatment of allergic conjunctivitis and also in the temporary relief of minor allergic symptoms of the eye. Common agents include antazoline sulfate, azelastine hydrochloride, cetirizine, chlorphenamine, emedastine, epinastine hydrochloride, ketotifen, levocabastine, loratadine and olopatadine. See hypersensitivity; mast cell stabilizers.

cetirizine
Zyrtec® Therapeutics A potent, antiinflammatory H1-receptor antagonist used for respiratory allergies; it has little CNS reactivity or cardiotoxicity and doesn't interact with other medicines. See Antihistamine.


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The risk for this overdose is highest with drugs that function by depressing the central nervous system, which include painkillers such as Brufen, anti allergy drugs like cetirizine and sedatives such as Valium.
A study in Germany in 1993 has shown that the stomach ulceration caused by the anti-inflammatory medications for arthritis was reduced by the administration of butterbur extract Cetirizine is a commonly prescribed prescription treatment for allergic conditions, and studies comparing that with butterbur demonstrated them to be equally effecting in reducing the symptoms typical of allergic reactions such as sneezing, runny nose and nasal congestion.
Clinical trials show butterbur toe-to-toe as effective as cetirizine (Zyrtec) and fexofenadine (Allegra) and with fewer side effects in treating seasonal allergies.
 
 
 
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