CLN5

(redirected from ceroid-lipofuscinosis, neuronal 5)

CLN5

A gene on chromosome 13q21.1-q32 that encodes a protein involved in the breakdown of post-translationally modified proteins in lysosomes.

Molecular pathology
CLN5 mutations have been linked to a clinical form of neuronal ceroid lipofuscinosis.
References in periodicals archive ?
Mutations in the ceroid-lipofuscinosis, neuronal 5 gene, and cathepsin D are believed to be responsible for NCL in border collies (31) and American bulldogs, (32,33) respectively.