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cerivastatin |
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cerivastatin,
an HMG-CoA reductase inhibitor (Baycol) withdrawn from the market in August 2001 after several cases of fatal rhabdomyolysis. cerivastatin [sĕ-riv´ah-stat″in] an inhibitor of an enzyme involved in the biosynthesis of cholesterol; used as an adjunct in the treatment of hyperlipidemia. Withdrawn in the United States because it is associated with an increased risk for rhabdomyolysis.
cerivastatin Baycol® Cardiology Cholesterol-lowering, HMG-CoA reductase inhibitor/statin for managing hypercholesterolemia and mixed dyslipidemia; it ↑ HDL-C and ↓ LDL-C; withdrawn from the market as it was linked to
rhabdomyolysis. See Statin. Want to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit the webmaster's page for free fun content. |
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Relative safety of gemfibrozil and fenofibrate in the absence of concomitant cerivastatin use. 34) The route from acetoacetyl-CoA to 7-dehydrocholesterol (Figure 1) (7) is the very route inhibited by HMG-CoA reductase inhibitors, namely the statin drugs atorvastatin, cerivastatin (withdrawn 8/01), fluvastatin, lovastatin, pravastatin, simvastatin, pitavastatin, and rosuvastatin, which were introduced to lower total cholesterol (TC) levels, and especially LDL-cholesterol (LDL-C) levels, ostensibly to prevent CVD. 14) Examples of international drug withdrawals have included fulminant liver failure with troglitazone, QT prolongation and ventricular arrhythmias with cisapride, haemolytic anaemia, coagulopathy and renal or hepatic dysfunction with temafloxacin, and fatal rhabdomyolysis with cerivastatin. |
cerivastatin |
Ceris CERISA cerise cerise cerise CERIST CERIT Cerite Cerite Cerithiacea CERIU cerium cerium cerium cerium Cerium dioxide cerium doped lutetium orthosilicate Cerium Doped Quartz cerium fluoride cerium metals cerium nitrate Cerium Oxide Cerium Oxide cerium stearate Cerium(IV) oxide Cerium(IV) oxide Cerium(IV) oxide cerium-140 cerium-142 cerium-144 cerivastatin Cerivastatin sodiumCerivastatin sodium CERJ CERL CERLA CERLAC CERLF CERLICO CERLIM CERLITYP CERLS CERM CerMA CERMACS Cermak Peterka Petersen, Inc. Cermak, Anton Cermak, Jaroslav Cermák, Jaroslav Cermak-Spirek furnace Cermanophile CERMAS CERMCS CERMEP Cermes cermet cermet cermet | ||||||||
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