Further studies showed that atorvastatin, cerivastatin
, fluvastatin, lovastatin and simvastatin stimulated cultured bone cells to make the osteogenic bone-morphogenic protein (BMP)-2.
25,26,41-43) In fact, the concurrent use of gemfibrozil (Lopid), a fibric acid derivative, was associated with 1/3 of rhabdomyolysis related deaths in patients using cerivastatin
Influence of Coenzyme Q(10) and Cerivastatin
on the Flow-Mediated Vasodilation of the Brachial Artery: Results of the ENDOACT Study," Int.
, which has been withdrawn, is also a substrate of CYPA34.
A noticeably downward monthly trend was observed across physician groups, likely reflecting the loss of marketshare to other statins, including the newly launched cerivastatin
Similarly, when pravastatin, simvastatin, atorvastatin, cerivastatin
, fluvastatin, and lovastatin were considered individually, none of the agents reduced the risk of cancer or cancer death.
Similarly, when pravastatin, simvastatin, atorvas-tatin, cerivastatin
, fluvas-tatin, and lovastatin were considered individually, none of the agents reduced the risk of cancer or cancer death.
(Baycol) was also a synthetic statin, but it was removed from the market because of side effects.
The anticholesterol drug cerivastatin
, sold under the brand name Baycol, was the most potent medicine in its class in the late 1990s.
Recently, a statin medication, cerivastatin
(Baycol[R]) was withdrawn due to its association with two deaths from rhabdomyolysis.
For instance, when the cholesterol-lowering cerivastatin
appeared on the market, there were already three similar drugs with a long history that could lower cholesterol and reduce heart attacks, After about six years on the market, cerivastatin
was withdrawn when it caused 52 deaths from severe muscle damage.
Results: The effect of the sterol-ester margarine (Take Control[R]) and cerivastatin
together was additive (39% reduction in LDL cholesterol).