cerebellar atrophy


Also found in: Dictionary.
Related to cerebellar atrophy: cerebellum, Cerebral atrophy

cer·e·bel·lar at·ro·phy

degeneration of the cerebellum, particularly the Purkinje cells, as the result of abiotrophy or exposure to toxic agents, as in alcoholism.

cerebellar atrophy

Etymology: L, cerebellum + Gk, a + trophe, without nourishment
deterioration and wasting of tissues of the cerebellum. Causes of the condition include nutritional and metabolic factors such as alcohol abuse and degenerative disease. See also spinocerebellar disorder.

cer·e·bel·lar at·ro·phy

(serĕ-belăr atrŏ-fē)
Degeneration of the cerebellum, particularly the Purkinje cells, as the result of abiotrophy or exposure to toxic agents, as in alcoholism.

cer·e·bel·lar at·ro·phy

(serĕ-belăr atrŏ-fē)
Degeneration of cerebellum due to abiotrophy or alcoholism.

cerebellar

pertaining to the cerebellum.

cerebellar abiotrophy
occurs in cattle, pigs and dogs. Affected young are normal at birth but at an early age ataxia and signs of cerebellar dysfunction appear, often progressing to complete immobilization. Cerebral function is usually normal. An inherited basis is suspected. In Kerry blue terriers, it is inherited as an autosomal recessive trait. Called also cerebellar neuronal abiotrophy.
cerebellar agenesis
absence of the cerebellum due to its non-appearance in the embryo.
cerebellar aplasia
see cerebellar atrophy (below).
cerebellar ataxia
the incoordination of gait characterized by exaggerated movements. There is no paresis. There is exaggerated strength and distance of movement—hypermetria. Caused usually by damage to the cerebellum or to the spinocerebellar tracts. May be congenital due to cerebellar atrophy or acquired due to inflammation or malacia of the cerebellum.
cerebellar atrophy
degeneration and loss of cells—Purkinje and granular cells of the cerebellum. Present at birth or soon after, is congenital in sheep, cattle, Arab horses, dogs and cats. Some of the diseases are inherited, some are known to be due to virus infection in utero, e.g. bovine virus diarrhea, feline panleukopenia. Some are in fact abiotrophies, premature aging of tissues. In the latter the animals are normal at birth but develop classical signs later. Segmental atrophy occurs in pigs but is asymptomatic.
cerebellar coning
see cerebellar lipping (below), brain herniation.
cerebellar cortex
the superficial gray matter of the cerebellum.
cerebellar dysfunction
see cerebellar ataxia (above).
cerebellar dysmelinogenesis
recorded in Chow Chow dogs; characterized by congenital head tremor.
feline cerebellar ataxia
see feline panleukopenia.
cerebellar hypomyelinogenesis
abnormally reduced myelination in the cerebellum; characterized clinically by severe neonatal tremor.
cerebellar hypoplasia
deficiency of cells of the cerebellum, the degree and distribution of which is variable. See cerebellar atrophy (above).
inherited cerebellar defects
includes cerebellar abiotrophy, atrophy, agenesis, hypoplasia, neuraxonal dystrophy.
cerebellar lipping
caused by diffuse cerebral edema. The vermis of the cerebellum protrudes through the foramen magnum and lies like a tongue over the medulla.
cerebellar neuronal abiotrophy
see cerebellar abiotrophy (above).
cerebellar neuraxonal dystrophy
reported in collie sheepdogs. The lesion is limited to axons and there are no lesions in the cerebellar folial neurons.
cerebellar syndrome
see cerebellar ataxia (above).
References in periodicals archive ?
The most characteristic radiographic finding of AT seen on computed tomography (CT) or MRI examination of the head is diffuse, progressive cerebellar atrophy, with atrophy of the vermis usually more prominent than that of the hemispheres (8) (Figure 1).
MRI yields cerebellar atrophy most prominent in the region of the vermis, with prominent folia and increased surrounding cerebrospinal spaces.
Cerebellar degeneration is found both in alcoholics with WKS and in those without it, but because WKS patients typically have a higher degree of cerebellar atrophy, it appears likely that thiamine deficiency also is the predominant cause of cerebellar degeneration.
2] Long-term therapy has been reported to cause cerebellar atrophy in humans.
All syndromes have some features that are chronic and/or progressive, such as muscle damage or cerebellar atrophy
Instead, Price asserts that O'Neill suffered from an ultimately lethal neurodegenerative disease--cortical cerebellar atrophy (CCA)--a disease of unknown origin that results in the progressive loss of key cells in the middle part of the cerebellum.
Bazille in 2005 showed cerebellar atrophy as a common finding in a series of three postmortem patients (8).

Full browser ?