centrosome


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centrosome

 [sen´tro-sōm]
a specialized area of condensed cytoplasm containing the centrioles and playing an important part in mitosis.

cy·to·cen·trum

(sī'tō-sen'trŭm),
A zone of cytoplasm containing one or two centrioles but devoid of other organelles; usually located near the nucleus of a cell.
[cyto- + G. kentron, center]

centrosome

/cen·tro·some/ (sen´tro-sōm) a specialized area of condensed cytoplasm containing the centrioles and playing an important part in mitosis.

centrosome

(sĕn′trə-sōm′)
n.
A small region of cytoplasm adjacent to the nucleus that contains the centrioles and serves to organize microtubules.

cen′tro·so′mic (-sō′mĭk) adj.

centrosome

Etymology: Gk, kentron + soma, body
a self-propagating cytoplasmic organelle present in animal cells and in those of some lower plants. The structure, which consists of the centrosphere and the centrioles, is located near the nucleus of the cell center or attraction sphere and functions as the dynamic center of the cell, especially during mitosis. Also called cytocentrum, microcentrum, paranuclear body.

centrosome

(1) Uncertain; possibly the microtubule organising centre (MTOC). 
(2) The smallest hypothetical unit of life, the cytocentrum.

cy·to·cen·trum

(sī'tō-sen'trŭm)
A zone of cytoplasm containing one or two centrioles but devoid of other organelles; usually located near the nucleus of a cell.
Synonym(s): centrosome, microcentrum.
[cyto- + G. kentron, center]

centrosome

A small mass of CYTOPLASM, lying near the nucleus of a cell and consisting of a pair of centrioles, which divides into two parts before cell division. These migrate to the poles of the cell and the spindle develops between them.

centrosome

an area of cell CYTOPLASM found near the nucleus, whose function is thought to be the organization of nuclear division since it is capable of assembling and disassembling MICROTUBULES. When nuclear division starts, the centrosome divides into two organizing centres which migrate to each pole (along with the CENTRIOLES, if present) and the spindle develops between them.

centrosome

a specialized area of condensed cytoplasm containing the centrioles and playing an important part in mitosis.
References in periodicals archive ?
96) In renal epithelial cells, at least part of fibrocystin/polyductin is localized to the renal epithelial primary cilium and the centrosome.
In 1991, we postulated a hypothesis that if a defective male centrosome is inherited by a human oocyte, it might lead to abnormal cleavage and compromise embryonic development (11).
Schatten, "The Centrosome and Its Mode of Inheritance: The Reduction of the Centrosome during Gametogenesis and Its Restoration during Fertilization," Developmental Biology 165 (1994): 299-335.
The new study by scientists at the University of California, San Francisco (UCSF) and Stowers Institute shows that Schmidtea mediterranea, which lives in southern Europe and Northern Africa, regenerates without centrosome, a structure long thought necessary for cell division
Katanin, a microtubule-severing protein, is a novel AAA ATPase that targets to the centrosome using a WD40-containing subunit.
Direct assessment of sperm centrosome function is difficult though scientists have used heterologous intracytoplasmic sperm injection (ICSI) technique.
The helix-loop-helix protein ID1 localizes to centrosomes and rapidly induces abnormal centrosome numbers.
There are a number of mechanisms that can give rise to numerical CIN, including centrosome amplification, spindle assembly checkpoint bypass, malfunctions in sister chromatid cohesion and abnormalities in kinetochore structure or function (42).
Researchers in his lab have used the wells to track the 3D position of the centrosome - the specialized region of a cell next to the nucleus that is the assembly point where the microscopic polymer tubes that serve as part of the cell's cytoskeleton are assembled before cell division and broken down afterwards.
Centrosome nucleated microtubule asters will be embedded into passive and active actin networks.
Brodsky and her colleagues traced this effect to a protein complex formed by one particular component of clathrin called CHC17, which directly stabilizes the centrosome and helps it mature.
These are arrays of MTs radiating from the centrosome, which fill up large portions of cells.