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centromere |
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centromere /cen·tro·mere/ (-mēr) the clear constricted portion of the chromosome at which the chromatids are joined and by which the chromosome is attached to the spindle during cell division.centromer´ic
Centromere The centromere is the constricted region of a chromosome. It performs certain functions during cell division. Mentioned in: Cri Du Chat Syndrome, Prader-Willi Syndrome centromere (cen) [sen′trəmir] Etymology: Gk, kentron + meros, part the constricted region of a chromosome that joins the two chromatids to each other and attaches to spindle fibers in mitosis and meiosis. During cell division the centromeres split longitudinally, half going to each of the new daughter chromosomes. The position of the centromere is constant for a specific chromosome and is identified as acrocentric, metacentric, submetacentric, or telocentric. Also called kinetochore, kinomere, primary constriction. centromeric, adj. centromere the clear constricted portion of the chromosome at which the chromatids are joined and by which the chromosome is attached to the spindle during cell division. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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Thereafter, we accomplished the hybridization using protein-nucleic acid probes (provided by DakoCytomation, Glostrup, Denmark) targeted against the centromeric region of the X chromosome (rhodamine-labeled) and the q-arm of the Y chromosome (labeled with fluorescein isothiocyanate). The Nature Methods article describes a whole-genome fractionation technique that can identify centromeric DNA in genomes, and suggests these techniques could be extended to crops and mammals. Serum antinuclear antibodies specific to Sm, double-stranded DNA, SSM/Ro, SSB/La, histone, RNP, Scl-70, Jo-1, and centromeric antigens were analyzed using Hep-2 nucleus antigens with the BINDAZYME ANA (antinuclear antibody) EIA Kit (The Binding Site, Birmingham, UK). |
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