centrilobular

(redirected from centrilobular necrosis)
Also found in: Acronyms.

centrilobular

 [sen″trĭ-lob´u-ler]
pertaining to the central portion of a lobule.

cen·tri·lob·u·lar

(sen'tri-lob'yū-lăr),
At or near the center of a lobule, for example, of the liver.

centrilobular

/cen·tri·lob·u·lar/ (sen″trĭ-lob´u-ler) pertaining to the central portion of a lobule.

centrilobular

[sen′trəlob′yələr]
Etymology: Gk, kentron + L, lobulus, small lobe
pertaining to the center of a lobule.

cen·tri·lob·u·lar

(sen'tri-lob'yū-lăr)
At or near the center of a lobule, e.g., of the liver.

centrilobular

Situated at the centre of a LOBULE of an organ, such as the liver.

centrilobular

pertaining to the central portion of a lobule.

centrilobular necrosis
necrosis restricted to the hepatocytes immediately surrounding the central venule. Called also periacinar necrosis.
References in periodicals archive ?
17] showed that, among vascular lesions observed after neoadjuvant chemotherapy, only the most severe cases (haemorrhagic centrilobular necrosis and regenerative nodular hyperplasia) were correlated with intraoperative transfusion requirements.
For example, with acute acetaminophen exposure, the process is acute hepatic centrilobular necrosis and repair; however, specific morphological diagnoses vary with time and dose.
APAP in excessive doses has a potential to cause a fatal hepatotoxicity due to hepatic centrilobular necrosis and has become an important problem (Larson et al.
The major pathologic findings were in the liver, which showed centrilobular necrosis, steatosis, and basophilic inclusion bodies in hepatocytes.
Effects of calcium channel blocking agents on calcium and centrilobular necrosis in the liver of rats treated with hepatotoxic agents.