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centrilobular
(redirected from centrilobular necrosis)

    Also found in: Acronyms 0.01 sec.
centrilobular /cen·tri·lob·u·lar/ (sen″trĭ-lob´u-ler) pertaining to the central portion of a lobule.
cen·tri·lob·u·lar (sntr-lby-lr)
adj.
Relating to or being at or near the center of a lobule, as of an internal organ.
centrilobular
[sen′trəlob′yələr]
Etymology: Gk, kentron + L, lobulus, small lobe
pertaining to the center of a lobule.
centrilobular [sen″trĭ-lob´u-ler]
pertaining to the central portion of a lobule.
centrilobular
pertaining to the central portion of a lobule.
centrilobular necrosis
necrosis restricted to the hepatocytes immediately surrounding the central venule. Called also periacinar necrosis.
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[17] showed that, among vascular lesions observed after neoadjuvant chemotherapy, only the most severe cases (haemorrhagic centrilobular necrosis and regenerative nodular hyperplasia) were correlated with intraoperative transfusion requirements.
Histological changes in the liver after chemotherapy by Julie, Catherine / Advances in Gastrointestinal Cancer
The livers showed centrilobular necrosis, with some inflammatory cellular infiltration and prominent inclusion bodies in the hepatocytes (Figure 2B).
Experimental infection of prairie dogs with monkeypox virus by Tesh, Robert B. / Emerging Infectious Diseases
For example, with acute acetaminophen exposure, the process is acute hepatic centrilobular necrosis and repair; however, specific morphological diagnoses vary with time and dose.
Tox/Path team takes on differential gene expression by Boorman, Gary / Environmental Health Perspectives
 
 
 
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