centrilobular emphysema


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cen·tri·lob·u·lar em·phy·se·ma

emphysema affecting the central portion of secondary pulmonary lobules, around the central bronchiole, typically involving the superior part of the lungs or lobes; may be related to inflammation of the bronchioles and to the effects of inhaled dust, which aggregates next to respiratory bronchioles; seen in coalworker's pneumoconiosis and (in mild form) asymptomatic city dwellers.

centrilobular emphysema

cen·tri·lob·u·lar em·phy·se·ma

(sen'tri-lob'yū-lăr em'fi-sē'mă)
Emphysema affecting the lobules around their central bronchioles, causally related to bronchiolitis, and seen in coal-miner's pneumoconiosis.
Synonym(s): centriacinar emphysema.
References in periodicals archive ?
Other findings included upper-lung-predominant centrilobular emphysema (57%; 12 of 21 patients) and patchy areas of decreased attenuation (38%; 8 of 21 patients) with lower-lung predominance.
Foci of centrilobular emphysema can be associated with fibrosis, as is well known to pathologists who work on COPD but is largely unknown outside this group.
However, alveolar wall fibrosis is also seen as a part of coexisting centrilobular emphysema (Figure 6).