centrilobular

centrilobular

 [sen″trĭ-lob´u-ler]
pertaining to the central portion of a lobule.

cen·tri·lob·u·lar

(sen'tri-lob'yū-lăr),
At or near the center of a lobule, for example, of the liver.

centrilobular

/cen·tri·lob·u·lar/ (sen″trĭ-lob´u-ler) pertaining to the central portion of a lobule.

centrilobular

[sen′trəlob′yələr]
Etymology: Gk, kentron + L, lobulus, small lobe
pertaining to the center of a lobule.

cen·tri·lob·u·lar

(sen'tri-lob'yū-lăr)
At or near the center of a lobule, e.g., of the liver.

centrilobular

Situated at the centre of a LOBULE of an organ, such as the liver.

centrilobular

pertaining to the central portion of a lobule.

centrilobular necrosis
necrosis restricted to the hepatocytes immediately surrounding the central venule. Called also periacinar necrosis.
References in periodicals archive ?
High-resolution CT of the chest in PVOD is characterized by 1) centrilobular ground-glass opacities, 2) septal lines, and 3) mediastinal lymphadenopathy.
Liver biopsy showed centrilobular necrosis with inflammatory cell infiltration compatible with a toxic etiology (Fig.
Incomplete compensation of enhanced hepatic oxygen consumption in rats with alcoholic centrilobular liver necrosis.
It has been reported that acetaminophen causes a potentially fatal, hepatic centrilobular necrosis when taken in overdose [18].
The radiologic findings are similar to those associated with pulmonary MZL and consist mainly of ground-glass attenuation, centrilobular nodules, thickening of broncho-vascular bundles, reticular shadows, and interlobular septal thickening in the peripheral lung.
In asthmatics, moderate-to-severe central bronchiectasis affecting 3 or more lobes, bronchial wall thickening, mucoid impaction, and centrilobular lung nodules are suggestive of allergic bronchopulmonary aspergillosis (ABPA) (Figure 2).
Thoracic computed tomography (CT) showed diffuse bilateral centrilobular lung nodules, paraaortic lymph node enlargement, and a small splenic lesion.
Serial level HRCT images reveal diffuse centrilobular nodular infiltrates and ground glass opacification (GGO) in both lung fields.
Dietary exposure to perfluorooctanoate or perfluorooctane sulfonate induces hypertrophy in centrilobular hepatocytes and alters the hepatic immune status in mice.
The prevalence of airways disease on CT (air trapping, bronchial wall thickening, bronchiectasis, and/or centrilobular opacities) was 77% in the autoantibody-positive preclinical RA group, compared with 31% of controls.
The liver exhibited diffuse centrilobular congestion and necrosis, and the kidneys exhibited bilateral cortical infarcts and acute tubular necrosis.
NYU School of Medicine researchers found an abundance of dendritic cells in the liver can protect the organ from acetaminophen damage while low levels of dendritic cells in the liver are associated with exacerbated liver damage, liver cell and tissue death, known as centrilobular hepatic necrosis, and acute liver failure from acetaminophen.