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centrilobular

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centrilobular /cen·tri·lob·u·lar/ (sen″trĭ-lob´u-ler) pertaining to the central portion of a lobule.
cen·tri·lob·u·lar (sntr-lby-lr)
adj.
Relating to or being at or near the center of a lobule, as of an internal organ.
centrilobular
[sen′trəlob′yələr]
Etymology: Gk, kentron + L, lobulus, small lobe
pertaining to the center of a lobule.
centrilobular
pertaining to the central portion of a lobule.
centrilobular necrosis
necrosis restricted to the hepatocytes immediately surrounding the central venule. Called also periacinar necrosis.


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Increases in liver weight, increases in serum levels of liver enzymes, centrilobular necrosis, fatty degeneration, hemosiderin-laden macrophages, and hemorrhage were seen in animals exposed to HC [ATSDR 1997; Fowler 1969; Gorzinski 1985; National Toxicology Program (NTP) 1989; Weeks et al.
Case report: hexachloroethane smoke inhalation: a rare cause of ... by Chen, Hong-I / Environmental Health Perspectives
The livers showed centrilobular necrosis, with some inflammatory cellular infiltration and prominent inclusion bodies in the hepatocytes (Figure 2B).
Experimental infection of prairie dogs with monkeypox virus by Tesh, Robert B. / Emerging Infectious Diseases
The histopathologic findings reveal discrete nonnecrotizing granulomas with centrilobular and bronchiolocentric distribution.
Hypersensitivity pneumonitis associated with environmental ... by Milton, Donald / Environmental Health Perspectives
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