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centrilobular

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centrilobular /cen·tri·lob·u·lar/ (sen″trĭ-lob´u-ler) pertaining to the central portion of a lobule.
cen·tri·lob·u·lar (sntr-lby-lr)
adj.
Relating to or being at or near the center of a lobule, as of an internal organ.

centrilobular
[sen′trəlob′yələr]
Etymology: Gk, kentron + L, lobulus, small lobe
pertaining to the center of a lobule.

centrilobular [sen″trĭ-lob´u-ler]
pertaining to the central portion of a lobule.

centrilobular
pertaining to the central portion of a lobule.

centrilobular necrosis
necrosis restricted to the hepatocytes immediately surrounding the central venule. Called also periacinar necrosis.


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Analysis of the impact of vascular lesions on outcome suggests that morbidity and mortality after liver surgery are not increased in patients with sinusoidal lesions but in the case of the most severe vascular lesions (hemorrhagic centrilobular necrosis, regenerative nodular hyperplasia), there is a higher risk of operative bleeding and a transfusion requirement [14,16].
7) Lastly, the observation of passive hepatic congestion in a centrilobular distribution illustrates the impaired hepatic venous drainage.
 
 
 
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