centriacinar

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Figure 4A shows that O-MWCNTs delivered by OPA caused centriacinar bronchiolitis/ alveolitis in mice in three of four labs (ML1, ML2, and ML3).

Histological evaluation of lung tissue sections demonstrated the presence of inflammatory cells within centriacinar regions similar to that observed in mice (data not shown).

Interlaboratory evaluation of rodent pulmonary responses to engineered nanomaterials: the NIEHS Nano GO Consortium

From this centriacinar position, fibrosis extends outward until it ultimately links adjacent bronchioles; at which time, the initial, predominantly peribronchiolar pattern of fibrosis may no longer be evident (Figure 9, B through D).

The upper lobes, on the other hand, exhibit earlier stages of asbestosis, with diffuse fibrosis confined to the centriacinar areas, and numerous asbestos bodies within or around the fibrotic lesions.

Pathology of asbestosis--an update of the diagnostic criteria: report of the Asbestosis Committee of the College of American Pathologists and Pulmonary Pathology Society

Depending on the anatomical location of airway destruction, emphysema can be classified into four major subtypes; centriacinar, panacinar, paraseptal and irregular (Kumar 2005).

Herbal medicine: role in the management of chronic obstructive pulmonary disease (COPD)

Further, the density Ki67-positive cells at distal perivascular-peribronchiolar areas and centriacinar regions was more prominent in [Il10.

Protective role of interleukin-10 in ozone-induced pulmonary inflammation

Atypical adenomatous hyperplasia consists of peripheral lesions, found in centriacinar regions close to terminal and respiratory bronchioles, that arise from bronchioloalveolar epithelium.

Update in neoplastic lung diseases and mesothelioma

The vast majority of exposed rats had little or no evidence of lung neutrophilia and centriacinar fibrosis (Finch et al.

Biodiesel exhaust: the need for health effects research

This conclusion is consistent with the time relationship of administration of TMP-SMZ and the clinical course, as well as with the transaminase increase and the histologic picture of massive centriacinar necrosis.

Acute Fulminant Hepatic Failure in a Woman Treated With Phenytoin and Trimethoprim-Sulfamethoxazole

Long-term exposure to ozone increases acute pulmonary centriacinar injury by 1-nitronaphthalene: I.

The role of inflammatory mediators in the synergistic toxicity of ozone and 1-nitronaphthalene in rat airways

Centriacinar (CAR) disease in the lungs of young adults: a preliminary report.

Assessing the public health benefits of reduced ozone concentrations. (Articles)

There was variable visible pigmentation, mostly along lymphatics in the subpleural interlobular septa, but also in some cases in the centriacinar zones and along the bronchopulmonary airways.

Distribution of Particulate Matter and Tissue Remodeling in the Human Lung

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