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central nervous system tumor

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central nervous system tumor,
a neoplasm of the brain or spinal cord that characteristically does not spread beyond the cerebrospinal axis, although it may be highly invasive locally and have widespread effects on body functions. Intracranial neoplasms are about four times more common than those arising in the spinal cord. From 20% to 40% of brain tumors are metastatic lesions from primary cancer elsewhere, such as in the breast, lung, GI tract, kidney, or a site of melanoma. See also brain tumor, spinal cord tumor.


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4 The World Health Organization (WHO) scheme for brain tumor classification and grading has been widely adopted worldwide, and it commonly serves as the recommended reference standard for central nervous system tumor research studies and clinical protocols as, for example, in the ''Protocol for the Examination of Specimens From Patients With Tumors of the Brain/Spinal Cord'' described by Parisi and colleagues in this issue of the ARCHIVES.
2007) showing that miR-34a is under-expressed in central nervous system tumors.
34) Certain polyoma viruses and several types of adenoviruses have been implicated as a cause of central nervous system tumors in laboratory animals, but research in humans has been inconclusive.
 
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