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central necrosis

   Also found in: Dictionary/thesaurus, Wikipedia, Hutchinson 0.09 sec.
central necrosis
n.
Necrosis involving the inner portions of a tissue or organ.
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l,7) Infiltration of the surface epithelium may give the tumor an ulcerated appearance, but central necrosis is rare.
Polymorphous low-grade adenocarcinoma of the parotid gland by Hessler, Richard B. / Ear, Nose and Throat Journal
The mediastinal lymph nodes were also strongly positive, accompanied by central necrosis.
Experimental infection of prairie dogs with monkeypox virus by Tesh, Robert B. / Emerging Infectious Diseases
In addition, intravital microscopy using a murine pseudo-orthotopic breast cancer model showed that NPI-2358 induces a rapid decrease in tumor blood flow resulting in tumor vascular collapse and central necrosis in established tumors.
Nereus Pharmaceuticals Reports Positive Preclinical Results of ... by Business Wire
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