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central necrosis

   Also found in: Dictionary/thesaurus, Legal, Encyclopedia, Wikipedia, Hutchinson 0.01 sec.
necrosis /ne·cro·sis/ (nĕ-kro´sis) pl. necro´ses   [Gr.] the morphological changes indicative of cell death caused by progressive enzymatic degradation; it may affect groups of cells or part of a structure or an organ.
aseptic necrosis  necrosis without infection, usually in the head of the femur after traumatic hip dislocation.
Balser's fatty necrosis  gangrenous pancreatitis with omental bursitis and disseminated patches of necrosis of fatty tissues.
caseous necrosis  cheesy n.
central necrosis  that affecting the central portion of an affected bone, cell, or lobule of the liver.
cheesy necrosis  that in which the tissue is soft, dry, and cottage cheese–like; most often seen in tuberculosis and syphilis.
coagulation necrosis  necrosis of a portion of some organ or tissue, with formation of fibrous infarcts, the protoplasm of the cells becoming fixed and opaque by coagulation of the protein elements, the cellular outline persisting for a long time.
colliquative necrosis  that in which the necrotic material becomes softened and liquefied.
contraction band necrosis  a cardiac lesion characterized by hypercontracted myofibrils and contraction bands and mitochondrial damage, caused by calcium influx into dying cells resulting in arrest of the cells in the contracted state.
fat necrosis  that in which the neutral fats in adipose tissue are split into fatty acids and glycerol, usually affecting the pancreas and peripancreatic fat in acute hemorrhagic pancreatitis.
liquefaction necrosis  colliquative n.
phosphorus necrosis  necrosis of the jaw bone due to exposure to phosphorus.
postpartum pituitary necrosis  necrosis of the pituitary during the postpartum period, often associated with shock and excessive uterine bleeding during delivery, and leading to variable patterns of hypopituitarism.
subcutaneous fat necrosis  induration of the subcutaneous fat in newborn and young infants.
necrosis ustilagi´nea  dry gangrene due to ergotism.
Zenker's necrosis  see under degeneration.

central necrosis
n.
Necrosis involving the inner portions of a tissue or organ.

central necrosis
Etymology: Gk, kentron, central, nekros, dead, osis, condition
death of the central part of a tissue or organ.

necrosis
pl. necroses [Gr.] the morphological changes indicative of cell death caused by enzymatic degradation.

aseptic necrosis
necrosis without infection or inflammation.
caseous necrosis
necrosis in which the tissue is soft, dry and cheesy, occurring typically in tuberculosis.
central necrosis
necrosis affecting the central portion of an affected bone, cell or lobule of the liver.
cheesy necrosis
that in which the tissue resembles cottage cheese; most often seen in tuberculosis.
coagulation necrosis
death of cells, the protoplasm of the cells becoming fixed and opaque by coagulation of the protein elements, the cellular outline persisting for a long time.
colliquative necrosis
see liquefactive necrosis (below).
liquefactive necrosis
necrosis in which the necrotic material becomes softened and liquefied.
moist necrosis
necrosis in which the dead tissue is wet and soft.
Zenker's necrosis
hyaline degeneration and necrosis of striated muscle; called also Zenker's degeneration.


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l,7) Infiltration of the surface epithelium may give the tumor an ulcerated appearance, but central necrosis is rare.
The mediastinal lymph nodes were also strongly positive, accompanied by central necrosis.
In addition, intravital microscopy using a murine pseudo-orthotopic breast cancer model showed that NPI-2358 induces a rapid decrease in tumor blood flow resulting in tumor vascular collapse and central necrosis in established tumors.
 
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