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central hypothyroidism

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central hypothyroidism
Endocrinology Hypothyroidism caused by pituitary or hypothalamic disease in the guise of tumors or vascular defects


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Any abnormality in hormone level is possible, though usually T3, T4, and FT1 are low and TSH could be low or normal, mimicking central hypothyroidism, but these patients usually have high cortisol levels.
Central hypothyroidism is hypothyroidism that results from a deficiency in either thyrotropin-releasing hormone (TRH) or thyrotropin (also called thyroid stimulating hormone, or TSR).
At 300 mg/m2/day, adverse events (AEs) of greater than or equal to 15 percent incidence, at least possibly related to treatment were hyperlipemia (primarily hypertriglyceridemia, 79 percent), hypercholesteremia (32 percent), central hypothyroidism (29 percent), headache 25 (percent), and asthenia (16 percent).
 
 
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