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The length of the pause serves to define and distinguish it from a central apnea.
Central apneas generally last 10-30 seconds followed by a 10-60 second crescendo hyperventilation.
Mixed apnea C a combination of central apnea and OSA; may result after longstanding OSA and the consequent development of central apnea
So every time one of our patients falls asleep they have a short central apnea or hypopnea to let the CO2 build up and every time they arouse, they breathe faster to get rid of the CO 2.
Hyperventilation causes central apnea, because you overshoot your carbon dioxide, and you stop breathing to restore it.
This type is called central apnea because it is related to the function of the central nervous system.
Episodes of central apnea, obstructive apnea with hypopnea, as well as disturbances in the sleep/wake cycle, are most common.
In mixed apnea, a period of central apnea is followed by a period of obstructive apnea before regular breathing resumes.
Preterm infants with bronchopulmonary dysplasia (BPD) had more central apneas, but fewer obstructive apneas in the prone, compared with supine position, however, there was little evidence of an interaction between the effect of sleep position and BPD status.
Observational studies indicate an increased prevalence of both obstructive and central apneas in HF patients and many patients may exhibit both OSA and central sleep apnea (CSA).
found that, in a relatively small study, 10 of 28 patients with TBI had sleep apnea and that the majority of these events were central apneas rather than obstructive apneas [87].
Most of the available literature on the development of sleep apnea following radiation has focused on obstructive sleep apnea, (11-13) but it should be kept in mind that central sleep apnea may also occur, as Udwadia et al noted in a report detailing radiation necrosis of the medulla with resultant central apneas.

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