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cell-mediated immune response

   Also found in: Dictionary/thesaurus, Acronyms, Encyclopedia, Wikipedia 0.02 sec.
cell-mediated immune response
n.
The immune response produced when sensitized T cells attack foreign antigens and secrete lymphokines that initiate the body's humoral immune response. Also called cell-mediated reaction, cellular immune response.

cell-mediated immune response,
a delayed reaction of the immune system, mediated primarily by sensitized T lymphocytes rather than antibodies. Cell-mediated immune response reactions are responsible for defense against certain bacterial, fungal, and viral pathogens; malignant cells; and other foreign proteins and tissues. Allergic dermatitis is an example of a cell-mediated immune response. Also called cellular hypersensitivity reaction, delayed hypersensitivity reaction, type IV hypersensitivity. Compare anaphylactic hypersensitivity.


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The cell-mediated immune response is critical for controlling such pathogens because their intracellular location shelters them from antibody binding.
Chronic beryllium disease is an occupational lung disease that begins as a cell-mediated immune response to beryllium.
These assassins, including natural killer cells, become part of the cell-mediated immune response.
 
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