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cell-mediated immune response

   Also found in: Dictionary/thesaurus, Acronyms, Encyclopedia, Wikipedia 0.01 sec.
cell-mediated immune response
n.
The immune response produced when sensitized T cells attack foreign antigens and secrete lymphokines that initiate the body's humoral immune response. Also called cell-mediated reaction, cellular immune response.

cell-mediated immune response,
a delayed reaction of the immune system, mediated primarily by sensitized T lymphocytes rather than antibodies. Cell-mediated immune response reactions are responsible for defense against certain bacterial, fungal, and viral pathogens; malignant cells; and other foreign proteins and tissues. Allergic dermatitis is an example of a cell-mediated immune response. Also called cellular hypersensitivity reaction, delayed hypersensitivity reaction, type IV hypersensitivity. Compare anaphylactic hypersensitivity.


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receptor blocking agents are useful for treating lymphocyte-mediated immunological diseases, and more particularly, for inhibiting Th1 cell-mediated immune responses.
5) An intact immune system is essential for the development of a positive skin test; conversely, any impairment of the cell-mediated immune response generally results in a minimal or absent reaction and thus a negative test.
The scientists have not yet evaluated the cell-mediated immune response in the volunteers, nor whether their antibodies can neutralize HIV in vitor.
 
 
 
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