cell-mediated hypersensitivity

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Related to cell-mediated hypersensitivity: Delayed Type Hypersensitivity

cell-mediated hypersensitivity

hypersensitivity initiated by antigen-specific T lymphocytes. Unlike forms of hypersensitivity mediated by antibodies, it takes one or more days to develop and can be transferred by lymphocytes but not by serum. The term is often equated with delayed hypersensitivity, although the latter is sometimes restricted to hypersensitivity involving cytokine-mediated reactions (as contrasted with direct cytolysis).


effected by cellular rather than chemical elements.

cell-mediated hypersensitivity
see delayed hypersensitivity.
cell-mediated immunity
see cellular immunity.
cell-mediated lympholysis assay
a test of cell-mediated immunity in which activated cytoxic T lymphocytes cause lysis of 51Cr-labeled target cells.