Printer Friendly
Dictionary, Encyclopedia and Thesaurus - The Free Dictionary
1,729,831,478 visitors served.
forum mailing list For webmasters
?
New: Language forums
Dictionary/
thesaurus
Medical
dictionary
Legal
dictionary
Financial
dictionary
Acronyms
 
Idioms
Encyclopedia
Wikipedia
encyclopedia
?

cell-mediated cytotoxicity

   Also found in: Dictionary/thesaurus, Wikipedia 0.02 sec.
cytotoxicity /cy·to·tox·ic·i·ty/ (si″to-tok-sis´ĭ-te) the degree to which an agent possesses a specific destructive action on certain cells or the possession of such action.cy´totoxic
antibody-dependent cell-mediated cytotoxicity  (ADCC) lysis of antibody-coated target cells by effector cells with cytolytic activity and Fc receptors.
cell-mediated cytotoxicity  cytolysis of a target cell by effector lymphocytes, such as cytotoxic T lymphocytes or NK cells; it may be antibody-dependent or independent.
cell-mediated cytotoxicity,
cytolysis of a target cell by effector lymphocytes, such as cytotoxic T lymphocytes or natural killer cells. It may be antibody-dependent (antibody-dependent cell-mediated cytotoxicity) or independent, as in certain type IV hypersensitivity reactions.


How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content.
?Page tools
Printer friendly
Cite / link
Email
Feedback
Add definition
? Mentioned in ? References in periodicals archive
 
The resulting product is expected to have target specificity similar to Rituximab (Rituxan([R]), Mabthera([R])) and to have relatively higher antibody dependent cell-mediated cytotoxicity, or ADCC.
GTC Biotherapeutics and LFB Biotechnologies Developing CD20 Antibody by Business Wire
Role of antibody-dependent cell-mediated cytotoxicity in the efficacy of therapeutic anti-cancer monoclonal antibodies.
Clinical Data Suggest ERBITUX(R) Recruits the Body's Immune System to ... by Business Wire
nbsp;of the antibody has been shown in previous studies to be responsible for mediating antibody-dependent cell-mediated cytotoxicity and has been the target of Xencor's XmAb technology.
Xencor Data Published in PNAS Show Engineering the ''Fc'' Region of ... by Business Wire
More results
 
Medical browser? ? Full browser
 
 
Medical Dictionary
?

Disclaimer | Privacy policy | Feedback | Copyright © 2009 Farlex, Inc.
All content on this website, including dictionary, thesaurus, literature, geography, and other reference data is for informational purposes only. This information should not be considered complete, up to date, and is not intended to be used in place of a visit, consultation, or advice of a legal, medical, or any other professional. Terms of Use.