To date, StemImmune has treated 25 cancer patients with its proprietary technology in a Phase 1 clinical trial that showed that its stem cell-mediated
immunotherapy was safe and well-tolerated with no adverse events reported, and demonstrated potential anti-tumor activity which supports further investigation in clinical trials.
Caption: The authors concluded that their findings indicated that cell-mediated
immunity is affected by the herpes zoster vaccine and enhanced by a stronger, or more recent, dose.
It was notable that among subjects who lost pertussis toxin antigen IgG, nearly half had retained cell-mediated
immunity to pertussis toxin, which may well have continued to protect them against the infection, Dr.
The goal of this study was to ascertain the cell-mediated
immune status of patients with NPC and to compare it with the status of patients with allergic rhinitis and normal controls.
Evidence indicates that the maternal immune system may tolerate fetal antigens by suppressing cell-mediated
immunity while retaining normal humoral immunity.
Type IV cell-mediated
allergies, the most common immune system reaction to latex, affect 82 percent of individuals allergic to rubber products.
Future research will focus on whether the antitumor effects of rhIL-12 can be enhanced through concomitant therapy with other cytokines that augment cell-mediated
immunity, he said.
immunity does the job with a white blood cell called the killer, or cytotoxic, T cell.
This mobilization is called cell-mediated
With knowledge of these vaccines' shortcomings in hand, Cambridge Biotech has developed an experimental "adjuvant" to boost the human body's cell-mediated
immunity to disease.
cytotoxicity (ADCC) is the main MOA of antibodies through which virus-infected or other diseased cells are targeted for destruction by components of the cell-mediated
immune system, such as natural killer cells.
receptor blocking agents are useful for treating lymphocyte-mediated immunological diseases, and more particularly, for inhibiting Th1 cell-mediated