This new program will focus on an undisclosed, first-in-class monoclonal antibody targeting a specific cell surface marker
implicated in an auto-immune ultra-orphan disease that primarily affects children.
Moreover, CD44 is the most prevalent cell surface marker
of cancer stem cells.
Other strategies being pursued include reprogramming of cancer stem cells and the targeting of a functional cell surface marker
in liver cancer stem cells, the aminopeptidase CD13.
ASC-1 (neutral amino acid transporter, y+ system, also called solute carrier family 7 member 10, slc7a10) was identified as a white fat--specific cell surface marker
In vitro assays, such as the efflux-based SP assay, ALDH activity assay, and cell surface marker
assays, have proven to be reproducible and straightforward methods of CSC detection.
Multiple myeloma cell lines and primary patient derived cells express the cell surface marker
Efalizumab is a recombinant humanized monoclonal antibody that binds to lymphocyte cell surface marker
CD11a, inhibiting the "activation and trafficking of T cells," according to Genentech Inc.
Using this cell surface marker
, the researchers have engineered a streamlined and simplified differentiation process to generate insulin-producing cells for future treatment of type 1 diabetes patients.
Despite the extensive information available in the literature, cell surface marker
signature of hAECs remains controversial so far.
During the next ten years, the main trend in cell surface marker
analysis will be further simplification of the sample preparation and the analysis itself.
Cell surface marker
analysis is also essential in determination of experimental drug or ligand response.
ViroTect[R](VR)and ViroTect[R](Tropism) combine cell surface marker
detection of immune cells with molecular detection of HIV replication in a single assay with multiplexed protein and nucleic acid measurements.