In some cases, germ cell nests
that were characteristic of female precursors could also be found in the center portions of lobes adjacent to the characteristic male precursor lobule structures.
Histologically, it is composed of squamoid solid cell nests
and cystic structures with a minor proportion of neuroendocrine cells (3-10) (Figure, A through E).
On electron microscopy it can present in a wide spectrum with basic patterns of tubules, cell nests
and cords attributable to ATE.
Scattered around and frequently surrounding the tumor cell nests
were large, multinucleated, pleomorphic tumor cells (syncytiotrophoblasts) (Figure 1, a and b).
Formation of cancer cell nests
and single cancer cells with bizarre nuclei in the stroma is definitive of invasive carcinoma (13).
Scattered S100positive sustentacular cells were seen at the periphery of the cell nests
2) Leiomyoblastomas have single file and sheet like pattern with epithelioid cell nests
, clear cytoplasmic halo and clear cell nests
Occasional foci of fused goblet cell nests
with signet ring cells were also seen.