cell lineage


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cell lineage

the developmental history of a cell from the ZYGOTE.
References in periodicals archive ?
A diagnosis of HLH requires either a molecular diagnosis consistent with HLH or the fulfillment of five of the following eight clinical, laboratory, and histopathological criteria: fever; splenomegaly; cytopaenia affecting at least two of three cell lineages in the peripheral blood; hypertriglyceridaemia and/or hypofibrinogenaemia; haemophagocytosis in the bone marrow, spleen, or lymph nodes; low or absent natural killer cell activity; hyperferritinaemia; and high levels of soluble-IL-2 receptor (Table).
Lymphomas are the diverse and complex group of neoplasms affecting lymphoreticular system5 and are classified based on cell lineage by 'The Revised Euro- pean American lymphoma' (REAL/WHO) system as : B cell malignancy ,T cell/natural killer malignancy and Hodgkin's lymphoma.
Interestingly, a subtype of human leukemias, CML (chronic myeloid leukemia), possesses self-renewal and cell lineage capabilities, and thereby the cells are assumed to be leukemia-initiating or cancer stem cells.
Embryonic stem cells (ESCs) are cells isolated from the inner cell mass of a blastocysts (5- to 7-day-old embryo) and represent the only truly totipotent cell lineage.
The resulting cell lineage - nicknamed 'HeLa' - is still growing strong today, helping scientists discover cures for everything from polio to Aids.
An example is the Paneth cell lineage, which emerges as the crypts form.
This includes, but is nor limited to, the study of general mechanisms of pattern formation and cell lineage, neural crest development, cell specification, differentiation, migration, and fate in early development of many organs/systems such as limb, nervous system, immune system, and heart.
Regeneration of sensory cells alter laser ablation in the lateral line system: Hair cell lineage and macrophage behavior revealed by time-lapse video microscopy.
Furthermore, 7 days, and especially 14 days, would be ample time to reveal changes in population numbers in any other hemopoietic and/or immune cell lineage in the bone marrow and spleen.
Although none of these latter three markers allows the simultaneous study of all types of malignant hemopoietic cells because they are restricted to a specific cell lineage or maturation-associated stage, these criteria produce a highly sensitive approach for the identification of leukemic cells in lymphoid neoplasias, especially when leukemic cells are present at low frequencies (46, 91).
The keys to unlock the paths cells to other cell lineage specifications from microRNA-deficient embryonic stem are still unknown, however.