Scientists were able to use this to prevent
cell death in living organisms.
Cell death can be classified according to its morphological appearance (which may be apoptotic, necrotic, autophagic or associated with mitosis), enzymological criteria (with and without the involvement of nucleases or of distinct classes of proteases, such as caspases, calpains, cathepsins and transglutaminases), functional aspects (programmed or accidental, physiological or pathological) or immunological characteristics (immunogenic or nonimmunogenic).
Mechanism of
cell death during warm hepatic ischemia-reperfusion in rats: apoptosis or necrosis?
The cytotoxic potential of arsenic trioxide leads to decreased mitochondrial membrane potential, fragmented DNA, and finally to apoptotic
cell death.
This result suggests that the intercellular channels joining the cytoplasm of the coupled cells must remain intact for longer than 40 min for bystander
cell death to occur.
In vitro apoptosis in individual cells was determined by terminal desoxyriboxyl-desoxyriboxyl transferase-mediated DVTP nick-end labeling (TUNEL) assay with the In Situ
Cell Death Assay Kit (Roche Diagnostic Corp.
The early discovery of the Bcl2 proto-oncogene and its subsequent linkage to apoptosis inhibition in human [Beta] cell lymphoma has led to the discovery of a number of additional structural homologs of Bcl-2 some of which function as apoptosis inducers subsequent to various
cell death signals.
In the study, xCELLigence System's recording of CI values allowed monitoring of primary cortical neuronal culture conditions, including plating, removal of glial cells, compound administration and
cell death profiling.
This is the one gene that regulates these two processes in cells, so now we can find targeted drugs to control the
cell death process," said Zhang.
When the mice were given antibodies that prevented transthyretin from interacting with the [beta]-amyloid protein, the mice showed typical brain
cell death.
ZIO-101 induces cell cycle arrest and
cell death by targeting several cellular pathways essential for cell survival.
Washington, Jan 25 (ANI): A new study has explained why some body organs are more susceptible to
cell death than others, which could eventually lead to advances in treating or preventing heart attack or stroke.