cell death


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Related to cell death: necrosis, apoptosis

cell death

the cessation of respiration within the cell that stops the production of energy, nutrients, active molecular transport, and the like.

cell death

1 terminal failure of a cell to maintain essential life functions. See also apoptosis, necrosis.
2 the point in the process of dying at which vital functions have ceased at the cellular level.
3 programmed cell death.

cell death

(sel deth)
Cessation of respiration within the cell that stops the production of energy, nutrients, active molecular transport, and the like.
References in periodicals archive ?
Scientists were able to use this to prevent cell death in living organisms.
The cytotoxic potential of arsenic trioxide leads to decreased mitochondrial membrane potential, fragmented DNA, and finally to apoptotic cell death.
As no component of WNV had been previously implicated in in vivo cell death of neuronal tissue, we reasoned that the WNV-Cp was a possible candidate, and we sought to investigate the effects of WNV-Cp in the brain in vivo.
There are 2 basic approaches to enhancing viability by inhibiting cell death: the cells may be engineered to stably express proteins such as Bcl-2 which thwart entry into apoptosis, or small molecule protease inhibitors may be added to the bioreactor to inhibit the key effectors of the cell death process.
The early discovery of the Bcl2 proto-oncogene and its subsequent linkage to apoptosis inhibition in human [Beta] cell lymphoma has led to the discovery of a number of additional structural homologs of Bcl-2 some of which function as apoptosis inducers subsequent to various cell death signals.
In the study, xCELLigence System's recording of CI values allowed monitoring of primary cortical neuronal culture conditions, including plating, removal of glial cells, compound administration and cell death profiling.
This is the one gene that regulates these two processes in cells, so now we can find targeted drugs to control the cell death process," said Zhang.
When the mice were given antibodies that prevented transthyretin from interacting with the [beta]-amyloid protein, the mice showed typical brain cell death.
Researchers have known for years that exposure to alcohol during the brain's growth spurt can ramp up cell death in rats and people.
IDUN Pharmaceuticals was originally founded in 1993 and focused on the discovery and development of small molecule drugs that act by modulating the products of cell death genes and on identifying new drug discovery targets within the cell death pathway.
The UC Davis team and their collaborators at the National Institutes of Health and Johns Hopkins University report that Bax, a factor known to promote cell death, is also involved in regulating the behavior of mitochondria, the structures that provide energy inside living cells.
The Laureates have identified key genes regulating organ development and programmed cell death and have shown that corresponding genes exist in higher species, including man," declared the award statement released by the Nobel Assembly at the Karolinska Institute in Sweden.

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