However, as shown in Table 2, in the case of the antibiotic cefuroxime axetil
, there are cheaper varieties available in the branded market than the JAS price.
TABLE 1 Recommended antibiotic doses for adults and children with localized Lyme disease (10) * Antibiotic Dose in adults Dose in children Doxycycline 100 mg po bid 4 mg/kg/d in 2 doses (for children [greater than or equal to] 8 years) Amoxicillin 500 mg po tid 50 mg/kg/d in 3 doses Cefuroxime axetil
500 mg po bid 30 mg/kg/d in 2 doses ([dagger]) Azithromycin 500 mg po daily 10 mg/kg/d (max: 500 mg/d) ([double dagger]) for 7-10 days Clarithromycin 500 mg po bid 7.
is an old antibiotic, so patents claiming the drug and its methods of use are ineligible for Orange Book-listing.
Some evidence indicates that cefpodoxime 400 mg and cefuroxime axetil
1 g might be oral alternatives.
Conclusions: These results support the conclusion that 5 days of treatment with telithromycin is as safe and effective in patients with ABMS as a 10-day course of treatment with amoxicillin-clavulanate or cefuroxime axetil
The most costly for 10day therapy include cefprozil, cefuroxime axetil
, and cefpodoxine proxetil and cefixime (Mason, 1996; Pichichero, 1994).
Orbus and Generics (UK) sign cefuroxime axetil
licensing and supply agreement
hexahydrate,Amitriptyline,Atropine Sulphate,Azelac acid 20%,Betamethosone Ear drops,Bimatoprost,Broad spectrum suncreen SPF, BuprenorpChlorthalidone hine, Carvedilol, cefuroxime axetil
Supply Of Drugs,acebrophylline,acitretin,acriflavin Glycerine,albendazole,aluminium Chloride hexahydrate,amitriptyline,atropine Sulphate,azelac Acid 20%,betamethosone Ear Drops,bimatoprost,broad Spectrum Suncreen Spf, Buprenorpchlorthalidone Hine, Carved
7,8,11) When treatment failures occur, the second choice of antibiotics includes amoxicillin-clavulanate, cefuroxime axetil
or intramuscular ceftriaxone.
06%) Alternatives: amoxicillin-clavulanate lg bd plus additional 500 mg amoxicillin bd or 2 g bd SR for 10 days * Antihistamines Cefpodoxime proxetil 200 - 400 mg bd for 10 days * Mucolytics (guaifenesin) Cefuroxime axetil
500 mg - 1g bd for 10 days Children * Zinc preparations not Amoxicillin 90 mg/kg/d in 3 recommended (anosmia) divided doses for 10 days Alternatives: amoxicillin-clavulanate 90 mg/ kg/d total amoxicillin in 2 or 3 divided doses for 10 days Cefpodoxime proxetil 8 - 16 mg/kg/d bd for 10 days Cefuroxime axetil
15 - 30 mg/kg bd for 10 days (Please see reference 9 for [beta] -lactam allergy and failed initial therapy) 3.
In adults without neurologic involvement, this includes a 28day course of 100 mg doxycycline twice daily, 500 mg amoxicillin three times daily, or 500 mg cefuroxime axetil
The most common comparison drugs were cefuroxime axetil
(5 studies) and amoxicillin clavulanate (5 studies).