cefuroxime


Also found in: Dictionary, Thesaurus, Legal, Encyclopedia, Wikipedia.
Related to cefuroxime: Cefuroxime axetil, Cefixime

cefuroxime

 [sef″u-rok´sēm]
a semisynthetic, β-lactamase–resistant, second-generation cephalosporinantibiotic effective against a wide range of gram-positive and gram-negative bacteria; used as the sodium salt and the axetil ester.

cefuroxime

/cef·u·rox·ime/ (sef″u-rok´sēm) a semisynthetic, β–resistant, second-generation cephalosporin effective against a wide range of gram-positive and gram-negative bacteria; used as the sodium salt and the axetil ester.

cefuroxime

(sĕf′yə-rŏk′sēm′)
n.
A broad-spectrum cephalosporin antibiotic given orally and parenterally for respiratory, skin, and other infections.

cefuroxime

A second-generation CEPHALOSPORIN antibiotic active against staphylococci and some Gram-negative organisms. It must be given by injection. Brand names are Zinacef and Zinnat.

antibiotic 

1. Pertaining to the ability to destroy or inhibit other living organisms.
2. A substance derived from a mould or bacterium, or produced synthetically, that destroys (bactericidal) or inhibits the growth (bacteriostatic) of other microorganisms and is thus used to treat infections. Some substances have a narrow spectrum of activity whereas others act against a wide range of both gram-positive and gram-negative organisms (broad-spectrum antibiotics). Antibiotics can be classified into several groups according to their mode of action on or within bacteria: (1) Drugs inhibiting bacterial cell wall synthesis, such as bacitracin, vancomycin and the β-lactams based agents (e.g. penicillin, cephalosporins (e.g. ceftazidime, ceftriaxone, cefuroxime). (2) Drugs affecting the bacterial cytoplasmic membrane, such as polymyxin B sulfate and gramicidin. (3) Drugs inhibiting bacterial protein synthesis, such as aminoglycosides (e.g. amikacin sulfate, framycetin sulfate, gentamicin, neomycin sulfate and tobramycin), tetracyclines, macrolides (e.g. erythromycin and azithromycin) and chloramphenicol. (4) Drugs inhibiting the intermediate metabolism of bacteria, such as sulfonamides (e.g. sulfacetamide sodium) and trimethoprim. (5) Drugs inhibiting bacterial DNA synthesis, such as nalixidic acid and fluoroquinolones (e.g. ciprofloxacin, levofloxacin, moxifloxacin, norfloxacin and ofloxacin). (6) Other antibiotics such as fusidic acid, the diamidines, such as propamidine isethionate and dibrompropamidine. Syn. antibacterial. See antiinflammatory drug; fusidic acid.

cefuroxime

a second generation cephalosporin antibiotic.
References in periodicals archive ?
While most isolates of Staphylococcus aureus were resistant to Norfloxacin (92%), Enterococcus faecalis was most resistant to the Cephalosporins like Cephalexin, Cefuroxime and Ceftriaxone [Table 4].
Cost-effectiveness ratios per expected cure were $5,265 for the azithromycin group and $6,145 for the cefuroxime group.
The Kenyan MDR isolates remained sensitive to co-amoxyclav, cefuroxime, gentamicin, nalidixic acid, and ciprofloxacin.
In these studies, FACTIVE tablets demonstrated excellent clinical response rates at test-of-cure visit for CAP and ABECB as good as comparators including clarithromycin, levofloxacin, amoxicillin/clavulanate, ceftriaxone and oral cefuroxime.
Our job is to defend Ranbaxy's ability to bring these products to market, and we are pleased that Ranbaxy has ultimately prevailed in bringing its cefuroxime axetil product to market over GSK's patent challenge," said William R.
is distributing cefuroxime axetil tablets in 250 mg and 500 mg dosage strengths.
Pseudomonas Aeruginosa (n= 2): - Nalidixic acid (100%), Nitrofurantoin (100%) > Cotrimoxazole (50%), Norfloxacin (50%) and all were susceptible to Cefuroxime, Gentamicin and Amikacin.
Vancomycin 30mcg, Azithromycin 15 mcg, Linezolid 30 mcg, Ampicillin 10mcg, Ciprofloxacin 5mcg, Cefuroxime 30mcg, Ceftriaxone 30 mcg, Aztreonam 30mcg.
For example, the cheapest branded cefuroxime axetil (500 mg) (antibiotic) in the market is almost three times cheaper than its JAS price.
Intravenous cefuroxime treatment was administered and intravenous insulin infusion was started for hyperglycemia.