cefotaxime


Also found in: Dictionary, Thesaurus, Wikipedia.

cefotaxime

 [sef´o-tak″sēm]
a third-generation cephalosporinantibiotic having a broad spectrum of activity, including against penicillinase-producing bacterial strains.

cefotaxime

/cef·o·tax·ime/ (-tak´sēm) a semisynthetic, broad-spectrum, β–resistant, third-generation cephalosporin effective against a wide variety of gram-negative bacteria but less active against gram-positive cocci than are the first- and second-generation cephalosporins; used as the sodium salt.

cefotaxime

(sĕf′ō-tăk′sēm′)
n.
A broad-spectrum cephalosporin antibiotic, C16H17N5O7S2, given intravenously in the form of its sodium salt.

cefotaxime

A third-generation CEPHALOSPORIN antibiotic active against Gram-negative organisms but not staphylococci. A brand name is Claforan.

cefotaxime

a third generation cephalosporin antibiotic.
References in periodicals archive ?
For confirmation of ESBL production ceftazidime (30ug), ceftazidime + clavulanic acid combination disc (30/10ug) manufactured by HiMedia and cefotaxime (30ug) + cefotaxime clavulanic acid (30/10ug) prepared in laboratory were used.
We found that 11 isolates were more resistant to cefotaxime (MIC [greater than or equal to] 256 [micro]g/mL) than to ceftazidime (MIC [less than or equal to] 128 [micro]g/mL), which suggests CTX-M-type enzymes.
Of these strains, 14 (42%) of 33 were resistant to cefotaxime.
Mineral oil 100% us gallon topical,1 gram cefotaxime sodium vial powder for injection iv,dimenhydrinate 50mg / 2ml injectable solution iv.
After co-cultivation, cotyledonary node explants were transferred to selective medium (MS + 2 mg L-1 6-BA + 2 mg L-1 AgNO3 + 300 mg L-1 cefotaxime + 50 mg L-1 kanamycin).
The antibiotic susceptibility disks Aztreonam (30g), Cefotaxime (30g), Ceftazidime (30g) and Ceftriaxone (30g) were placed on Mueller Hinton agar.
For bacteria isolated from diabetic foot infection, the following antibiotics were used against the causative agents: amikacin (30ug), (20ug of amoxicillin + 10ug of clavulanate), cefotaxime (30ug), ceftazidime (30ug), ciprofloxacin (5ug), erythromycin (15ug), gentamycin (10ug), oxacillin (1ug), piperacillin (100ug) and vancomycin (30ug).
were showed 100% sensitivity to Cefotaxime whereas complete resistance to Penicillin G and Amikacin were observed for Gram negative bacterial isolates.
Detection of extended spectrum beta lactamases was done by using Ceftazidime (30 [micro]g) and Ceftazidime (30 [micro]g)/Clavulanic acid (10 [micro]g) and Cefotaxime (30[micro]) and Cefotaxime (30 [micro]g)/Clavulanic acid (10 [micro]g).
Sensitivity of gram-negative and gram-positive organisms to cefotaxime was 8.
Since the first report from Spain in 2000 of strains producing CTX-M-9 (6), which confers resistance to cefotaxime, various CTX-M-type ESBLs have been identified in Salmonella Virchow.