cefepime


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Related to cefepime: Cefixime

cefepime

 [sef´ĕpēm]
a semisynthetic fourth-generation cephalosporinantibiotic; used in the treatment of infections of the skin and soft tissues and of the respiratory and urinary tracts. Administered intravenously or intramuscularly as the hydrochloride salt.

cefepime

/cef·e·pime/ (sef´ĕpēm) a fourth-generation cephalosporin antibiotic; used as the hydrochloride salt.

cefepime

(sĕf′ə-pēm′)
n.
A broad-spectrum cephalosporin antibiotic, C19H24N6O5S2, used in its hydrochloride form to treat a variety of infections, including skin and urinary tract infections and certain types of pneumonia.

cefepime

a fourth-generation cephalosporin.
indications It is used to treat infections caused by gram-negative bacilli, including Escherichia coli, Proteus, and Klebsiella; gram-positive organisms, including Streptococcus pneumoniae, S. pyogenes, and Staphylococcus aureus; and infections of the lower respiratory tract, urinary tract, skin, and bone.
contraindications Known hypersensitivity to cephalosporins prohibits its use. It also should not be used in infants less than one month old.
adverse effects Life-threatening effects include nephrotoxicity, renal failure, leukopenia, thrombocytopenia, agranulocytosis, neutropenia, lymphocytosis, eosinophilia, pancytopenia, hemolytic anemia (rare), and anaphylaxis. Other serious effects include GI bleeding; increased aspartate aminotransferase (AST), alanine aminotransferase (ALT), bilirubin, lactic dehydrogenase, and alkaline phosphatase; proteinuria, candidiasis, increased blood urea nitrogen, and thrombophlebitis. Common side effects include nausea, vomiting, diarrhea, and anorexia.

cefepime

Maxipime® Infectious disease A 4th-generation cephalosporin Indications RTIs–eg bronchitis, pneumonia; cellulitis and other skin and soft-tissue infections; UTIs–eg pyelonephritis, febrile neutropenia, PID, gonorrhea, septicemia, intra-abdominal infections, meningitis, surgical prophylaxis. See Cephalosporin.

cefepime (sef´əpēm),

n brand name: Maxipime;
drug class: fourth-generation cephalosporin;
action: inhibits cell wall synthesis in sensitive organisms and is bactericidal;
uses: respiratory tract, urinary tract, and skin and other soft tissue infections associated with gram-negative organisms.

cefepime

a fourth generation cephalosporin antibiotic.
References in periodicals archive ?
In our study, the antibiotic resistances among Gram-negative bacteria isolated from gill samples at high resistance rates were detected especially for the ampicillin, piperacillin, and cephalosporin-group antibiotics and the meropenem, cefepime, and ceftazidime.
The patient's antibiotic therapy was deescalated to vancomycin and cefepime on POD#29.
No resistance was observed in case of Cefepime + Tazobactam and Amikacin (Table 3).
Cefepime was inititated by evaluating the undelying clinical picture.
El cefepime es un antibiotico betalactamico perteneciente a Ias cefalosporinas de cuarta generacion y ampliamente utilizado para el tratamiento de infecciones graves (1,2).
Rates of resistance in a 2006 study from SA private laboratories showed 52% resistance to cefuroxime, 46% to ceftriaxone and 44% to cefepime.
Paciente masculino de 46 anos, quien se encontraba en hospitalizacion domiciliaria en manejo de espondilodiscitis posterior a laminectomia L4-L5 por hernia discal, en manejo con vancomicina 1 gr intravenoso/12 horas y cefepime 1 gr intravenoso/12 horas, que venia recibiendo durante los 25 dias previos a la fecha de ingreso, antibiotico empirico indicado por infectologia por 42 dias.