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Related to cefepime: Cefixime
cefepime/cef·e·pime/ (sef´ĕpēm) a fourth-generation cephalosporin antibiotic; used as the hydrochloride salt.
A broad-spectrum cephalosporin antibiotic, C19H24N6O5S2, used in its hydrochloride form to treat a variety of infections, including skin and urinary tract infections and certain types of pneumonia.
a fourth-generation cephalosporin.
indications It is used to treat infections caused by gram-negative bacilli, including Escherichia coli, Proteus, and Klebsiella; gram-positive organisms, including Streptococcus pneumoniae, S. pyogenes, and Staphylococcus aureus; and infections of the lower respiratory tract, urinary tract, skin, and bone.
contraindications Known hypersensitivity to cephalosporins prohibits its use. It also should not be used in infants less than one month old.
adverse effects Life-threatening effects include nephrotoxicity, renal failure, leukopenia, thrombocytopenia, agranulocytosis, neutropenia, lymphocytosis, eosinophilia, pancytopenia, hemolytic anemia (rare), and anaphylaxis. Other serious effects include GI bleeding; increased aspartate aminotransferase (AST), alanine aminotransferase (ALT), bilirubin, lactic dehydrogenase, and alkaline phosphatase; proteinuria, candidiasis, increased blood urea nitrogen, and thrombophlebitis. Common side effects include nausea, vomiting, diarrhea, and anorexia.
cefepimeMaxipime® Infectious disease A 4th-generation cephalosporin Indications RTIs–eg bronchitis, pneumonia; cellulitis and other skin and soft-tissue infections; UTIs–eg pyelonephritis, febrile neutropenia, PID, gonorrhea, septicemia, intra-abdominal infections, meningitis, surgical prophylaxis. See Cephalosporin.
a fourth generation cephalosporin antibiotic.