Prophylactic antibiotics for various surgical procedures Type of surgery Consensus position Abdominal or vaginal Cefazolin
8%) Amox/clav ([dagger]) 0 of 2 (0%) 0 of 26 (0%) Cefazolin
0 of 2 (0%) 0 of 26 (0%) Oxacillin 0 of 2 (0%) 0 of 26 (0%) Penicillin 0 of 2 (0%) 0 of 26 (0%) * Trimethoprim/sulfamethoxazole.
4] Cefotetan disodium (Stuart Pharmaceuticals, Wilmington, Del) and cefazolin
sodium (SmithKline Beecham Pharmaceuticals, Philadelphia, Pa) were adjusted to a concentration of 1 mg/mL using phosphate-buffered saline (pH 7.
The most common combinations were 6% cefazolin
with ciprofloxacin, 3% cefazolin
with TMP-SMX, 2% cefazolin
with gentamicin, and 1% ciprofloxacin with gentamicin.
Braun the first company to deliver an FDA-approved 2g Cefazolin
dose to hospitals and other healthcare settings where it is a frequently prescribed antibiotic.
Steroids (administer all three regimens): Dexamethasone 20 mg intravenously at presentation Methylprednisolone 80 to 120 mg intramuscularly (buttock) at presentation Prednisone 60 to 80 mg orally every morning for 10 days at home Hydration: 5% dextrose in lactated Ringer's solution 1 to 2 L intravenously at presentation Force fluids 2 L/day orally at home Antibiotics: Cefazolin
2 g intravenously at presentation Cephalexin 500 mg orally four times daily for 10 days at home Analgesia: Ketorolac and a narcotic intravenously at presentation Narcotic pain medications orally at home Other: Warm salt-water gargles hourly at home ENT follow-up in 48 to 72 hours if the patient does not improve Admit if any airway distress is noted
is recalling four lots of the drug cefazolin
for injection because of the possibility of microbial contamination, which may pose a serious or life-threatening risk for some patients.
In our institution, second-generation cephalosporin results are reported only if the organism is resistant to cefazolin
, and third-generation drugs are reported only if the isolate is resistant to both cefoxitin and cefamandole.
Braun now offers a broad spectrum of intravenous cephalosporin antibiotic therapies for the hospital setting: Cefoxitin, CefTRIaxONE, Cefazolin
, CefUROXime and Cefotetan.
pneumoniae Test/antimicrobial agent N10-0469 Broth microdilution (MIC, [micro]g/mL) Amoxicillin/clavulanic acid >32 Piercillin/tazobactam >64 Ampicillin >16 Cefazolin
>16 Cefotaxime >64 Cefotaxime/clavulanic acid >64 Ceftazidime >128 Ceftazidime/clavulanic acid >128 Cefepime >16 Cefoxitin >64 Imipenem >16 Meropenem >8 Chloramphenicol 16 Tetracycline >32 Amikacin >64 Gentamicin >16 Ciprofloxacin >2 Trimethoprim/sulfamethoxazole >4 Etest (MIC, [micro]g/mL) Aztreonam >256 Imipenem >32 Meropenem >32 Ertapenem >32 Colistin 0.
The women were randomized to either 1 g of cefazolin
or placebo given 30 minutes before the procedure.
, piperacillin/tazobactam and clindamycin, all in injectable form, are routinely used to treat these infections regardless of the intent -- empiric or documented.