caveolin


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cav·e·o·lin

(kav'ē-ō-lin),
The 22-kD transmembrane protein associated with the membranes of caveolae and with Golgi membranes; believed to function in signal transduction, in cholesterol transport, and metabolism of the cell.
References in periodicals archive ?
The increased levels of caveolin 1 in MVE has a cardioprotective effect in ischemia/reperfusion-induced damage, probably due to the increased endothelial NO release [5].
Caveolin-1 is the most important protein in the caveolin family (Frank et al.
The analysis of mean densitometric ratios of caveolin, Hsp90, and porin to eNOS protein respectively was performed by using NIH's Image J64 software (see URL above).
The Effect of Changes in Caveolin and Cholesterol Levels on Cellular and Mitochondrial Oxidative Stress and Mitochondrial Swelling.
Hypercholesterolemia decreases nitric oxide production by promoting the interaction of caveolin and endothelial nitric oxide synthase.
In addition, VEGF, maspin, osteopontin, integrin [beta]4, caveolin 1 and 2, and P-cadherin have all been reported to be expressed preferentially in breast cancers with basal-like morphology.
Nine candidates failed the initial criteria, such as assay length or unsuitable CpG site location for primer and probe placement [BCOR, BCL6 co-repressor; CAV1, caveolin 1, caveolae protein, 22kDa; CD44, CD44 molecule (Indian blood group); CDH13, cadherin 13, H-cadherin (heart); VCAN (formerly CSPG2), versican; FCGR2A, Fc fragment of IgG, low affinity IIa, receptor (CD32); GSK3B, glycogen synthase kinase 3 beta; PCDH17, protocadherin 17; and TAF11, TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa].
Distribution and significance of caveolin 2 expression in normal breast and invasive breast cancer: an immunofluorescence and immunohistochemical analysis.
Galbiati, "Inhibition of thioredoxin reductase 1 by caveolin 1 promotes stress-induced premature senescence," EMBO Reports, vol.
These include CD109, (4,5) caveolin 1 and 2, (6,7) podoplanin, (8) P-cadherin, (9,10) maspin, (11-13) nestin, (14) p75, (15-17) 14-3-3 sigma (stratifin), (18) smooth muscle actin (SMA), (19) p63, (20) CD10, (21) smooth muscle myosin heavy chains (SMMHCs), (22,23) h-caldesmon, (23) calponin, (23) S100, (24-26) basal type and high-molecular-weight cytokeratins, (27) glial fibrillary acid protein, (28,29) metallothionein, (12) Wilms tumor 1 protein, (30) CD44s, (31) and vimentin, (32) among others.
Our study results suggest that iroxanadine promotes healing by normalizing endothelial dysfunction through the molecular chaperone amplification pathway, as well as releasing endothelial nitric oxide synthase (eNOS) from its negative regulator caveolin.