catabolite (gene) activator protein

(redirected from catabolite gene activator)

ca·tab·o·lite (gene) ac·ti·va·tor pro·tein (CAP),

a protein that can be activated by cAMP, whereupon it affects the action of RNA polymerase by binding it with it or near it on the DNA to be transcribed.

ca·tab·o·lite (gene) ac·ti·va·tor pro·tein

(CAP) (kă-tab'ō-līt jēn ak'ti-vā-tŏr prō'tēn)
A protein that can be activated by cAMP, whereon it affects the action of RNA polymerase by binding with it or near it on the DNA to be transcribed.
Synonym(s): cAMP receptor protein.
References in periodicals archive ?
Irene Weber continued her investigation of the catabolite gene activator protein that she had started during her postdoctoral studies with Dr.
Irene Weber continued her structural investigation of the Escherichia coli catabolite gene activator protein (CAP).
Steitz, Structure of a Complex of Catabolite Gene Activator Protein and Cyclic AMP Refined at 2.
Weber, Crystal Structure of a cAMP Independent Form of Catabolite Gene Activator Protein with Adenosine Substituted in One cAMP-Binding Site, Biochemistry 28 (11), 45684574 (1989).