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catabolic disease

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catabolic disease
Catabolic illness Metabolic disease A condition characterized by rapid weight loss and loss of fat and skeletal muscle mass, which may occur in a background of either an acute, self-limited disease–eg, injury, infection or a chronic condition–eg DKA, multisystem organ failure, AIDS, advanced CA, chemotherapy, RT Associated clinical events Immunosuppression, muscle weakness, predisposition to PTE, thrombophlebitis, altered stress response Management Aggressive nutritional support in CI may not prevent protein loss; specialized nutrition–eg, glutamine, arginine, branched-chain amino acids, n-3–omega-3 fatty acids, growth hormone, possibly IGF-I and EGF, may ↓ protein loss, hospitalization


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15-17 Potential areas of further research may include the combination of BCAA (branched-chain amino acids) supplements with other anabolic factors (eg, GH) in managing patients with catabolic disease states.
Whereas Celtrix already owns specific intellectual property relating to the systemic treatment of osteoporosis, catabolic diseases, wound healing, trauma, burns, as well as certain hematologic and renal indications, this new patent claims the use of SomatoKine to deliver IGF-I at dose levels that the company believes are necessary for efficacy.
 
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