caspase-cleavage

caspase-cleavage

The intracellular activation of caspase enzymes so that they propagate a signalling cascade leading to the cleavage of particular intracellular proteins in the process of APOPTOSIS. The blood levels of the caspase-cleavage product of cytokeratin 18, which is abundant in liver cells, provides a measure of hepatocyte apoptosis.
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