caspase 10

caspase 10

A protein encoded by CASP10, a gene on chromosome 2q33-q34, that belongs to the cysteine-aspartic acid protease (caspase) family, which cleaves and activates caspases 3 and 7 and, in concert, play a central role in the execution phase of apoptosis.
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The apoptotic proteases MCH4 and MCH5 (which are also known as caspase 10 and caspase 8, respectively) were co-discovered by Idun scientists and scientists at Thomas Jefferson University in Philadelphia, Pennsylvania.

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