CASP1

(redirected from caspase 1, apoptosis-related cysteine peptidase)

CASP1

A gene on chromosome 11q23 that encodes a protein belonging to the cysteine-aspartic acid protease (caspase) family which, once activated by proteolytic processing, plays a central role in the execution-phase of cell apoptosis, as well as various stages of embryological development.

Molecular pathology
CASP1 mutations may play a role in Huntington’s disease.
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