case-control study

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Related to case-control study: cross-sectional study, Cohort study

case-control study

a nonexperimental research design using an epidemiological approach in which previous cases of the condition are used in lieu of new information gathered from a randomized population. A group of patients with a particular disease or disorder, such as myocardial infarction, is compared with a control group of persons who have not had that medical problem. The two groups, matched for age, sex, and other personal data, are examined to determine which possible factor (e.g., cigarette smoking, coffee drinking) may account for the increased disease incidence in the case group. See also retrospective study.

case-con·trol study

(kās-kŏn-trōl stŭdē)
Epidemiologic method that begins by identifying people with a disease or condition of interest and compares their past history of exposure to identified or suspected risk factors with the past history of similar exposures among those who resemble the cases but do not have the disease or condition of interest.

case-control study,

n an investigation employing an epidemiologic approach in which previously existing incidents of a medical condition are used in lieu of gathering new information from a randomized population. Control is obtained by comparing known cases of the medical condition with a group of persons who have not developed the medical problem.


in epidemiology, an animal which has the specified disease or condition which is under investigation.

case abstract
a structured summary of a case report suitable for computer entry; permits machine sorting and retrieval and leads an investigator to the original paper records on which detailed descriptions must be based.
case-control sampling
selection of cases as a sample to use in a case-control study (below).
case-control study
a retrospective, analytical, epidemiological study. A group of pre-existing cases of the disease are matched with a selected group of control animals that do not have the disease so that the presence or otherwise of an hypothesized disease determinant can be ascertained in both groups.
case fatality rate
the proportion of cases with a specified condition which die within a specified time.
case finding
the strategy of surveying a population to find the sick animals that are the foci of infection; an essential early step in the eradication of any disease.
case history
the collected data concerning an individual, contact and related animals, environment and management procedures, including any past medical history and any other information that may be useful in analyzing and diagnosing the case or for instructional or research purposes.
index case
the first case recorded in an outbreak.
case management
care of a sick animal including specific and supportive medication, surgical intervention, housing, bedding, nutrition, restraint, collection of specimens for submission to laboratory or stall-side tests.
case population
the group of animals in the total population which are sick or infected, as distinct from the control population, which are not sick or infected.
case recording
entry in records of the clinical findings of individual sick animals. May be structured or unstructured, paper or machine, with or without the accounting record for the case.
References in periodicals archive ?
It is apparent that the GIS study provided greater power to detect the geographic effect than did the case-control study.
The authors, led by Sophie Billioti de Gage of Universite de Bordeaux (France), conducted a nested case-control study of 1,796 members of a public drug plan in Quebec, Canada, aged 66 years and older who had been diagnosed with Alzheimer's disease (AD) at least 6 years prior, and more than 7,000 non-Alzheimer's controls matched for age and sex.
Data source: Nested case-control study of 1,102 women aged 20-49 years diagnosed with invasive breast cancer, compared with 21,755 controls.
Harbin, China, was the site of a lung cancer case-control study (n = 654) that, controlling for multiple potential confounding factors, found that lung cancer was associated with the use of coal for fuel as well as for cooking (Galeone et al.
Investigating matched case-control study designs with causal effect estimation.
Data Source: A case-control study including 135 Barrett's esophagus patients, 135 controls with gastroesophageal reflux disease, and 932 controls undergoing colonoscopies.
After a results of a case-control study that found an association between CJD and medical procedures was reported from Japan in 1982 (2), 132 patients with dura mater graft-associated CJD (dCJD) have been found in Japan (11,12); however, no recent studies have investigated medical procedures as a risk for acquiring sCJD.
Research: A case-control study was conducted to examine several dietary hypotheses regarding the etiology of ovarian cancer in a population with a broad range of dietary intakes.
What the researchers did was a case-control study -- the infants were paired for sex, age, geography, health history, socio-economics, pets, family size and sibling school attendance.
at the MUHC, and Professor Philippe Froguel from the Division of Medicine at Imperial College London, this case-control study of 392,935 single-nucleotide polymorphisms (SNPs) revealed that patients who developed type-2 diabetes shared common gene variations on chromosomes 8, 10, and 11.
Although those estimates are unstable because of the low number of events, a case-control study of nearly 10,700 infants with a major congenital abnormality and more than 21,500 healthy controls also showed no significant association between lithium and congenital abnormalities.
In a case-control study comparing 65 patients with rosacea with 65 control subjects, Dr.