cartilage oligomeric matrix protein


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cartilage oligomeric matrix protein

a member of the trombospondin gene family, it is expressed at high levels in the matrix of chondrocytes. Mutations in the cartilage oligomeric matrix protein gene, COMP, [MIM*600310], result in pseudoachondroplasia and multiple epiphysial dysplasia.
References in periodicals archive ?
Novel cartilage oligomeric matrix protein (COMP) neoepitopes identified in synovial fluids from patients with joint diseases using affinity chromatography and mass spectrometry.
Aggrecan and cartilage oligomeric matrix protein in serum and synovial fluid of patients with knee osteoarthritis.
Cartilage oligomeric matrix protein (COMP) levels in serum and synovial fluid in osteoarthritis (OA) patients: Correlation with clinical, radiological and laboratory parameters.
Serum cartilage oligomeric matrix protein reflects the presence of clinically diagnosed synovitis in patients with knee osteoarthritis.
Diurnal variation in serum levels of cartilage oligomeric matrix protein in patients with knee osteoarthritis or rheumatoid arthritis.
2009) Changes in serum cartilage oligomeric matrix protein (COMP), plasma CPK and plasma hs-CRP in relation to running distance in a marathon (42.
2005) Serum concentration of cartilage oligomeric matrix protein (COMP) is sensitive to physiological cyclic loading in healthy adults.
1997) Small fragments of cartilage oligomeric matrix protein in synovial fluid and serum as markers for cartilage degradation.
2010) Different mechanical loading protocols influence serum cartilage oligomeric matrix protein levels in young healthy humans.
Pseudoachondroplasia and multiple epiphyseal dysplasia due to mutations in the cartilage oligomeric matrix protein gene.
Serum cartilage oligomeric matrix protein (sCOMP) is elevated in patients with knee osteoarthritis: a systematic review and meta-analysis.
The role of cartilage oligomeric matrix protein (COMP) in skeletal disease.

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