cartilage oligomeric matrix protein


Also found in: Acronyms, Wikipedia.

cartilage oligomeric matrix protein

a member of the trombospondin gene family, it is expressed at high levels in the matrix of chondrocytes. Mutations in the cartilage oligomeric matrix protein gene, COMP, [MIM*600310], result in pseudoachondroplasia and multiple epiphysial dysplasia.
References in periodicals archive ?
ADAMTS-12 associates with and degrades cartilage oligomeric matrix protein.
Deoxypyriclinoline in urine and cartilage oligomeric matrix protein in serum were quantitated by ELISA.
Serum or plasma cartilage oligomeric matrix protein concentration as a diagnostic marker in pseudoachon-droplasia: Differential diagnosis of a family.
Major Finding: At 6 months after bariatric surgery, patients had a 20% drop from baseline BMI and their average serum level of procollagen type II N-terminal propeptide (PIIANP), a marker of cartilage synthesis, had risen 32%, while their average serum level of cartilage oligomeric matrix protein (COMP) had decreased by 36%.
Retention of cartilage oligomeric matrix protein (COMP) and cell death in redifferentiated pseudoachondroplasia chondrocytes.

Full browser ?