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carnitine deficiency |
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carnitine coenzyme of fatty acid oxidation and acetyl transfer; often designated vitamin BT, due to its vitamin role in Tenebrio sp. Present in high concentrations (5% dry weight) in meat extracts. carnitine acetyltransferase enzyme associated with buffering of acetyl groups from acetyl CoA. carnitine deficiency
associated with myocardial disease in dogs, particularly Boxers. carnitine deficiency Metabolic disease A condition caused by ↓ carnitine palmityl transferase, failure of carnitine transport in kidney, muscle, fibroblasts or cobalamin deficiency, electron transfer flavoprotein deficiency, Fanconi
syndrome, isovaleric acidemia, medium chain acylCoA dehydrogenase deficiency, methylmalonic and propionic acidemias; Pts receiving valproate for seizure disorders may develop a toxicity syndrome with associated carnitine deficiency Clinical
Myoglobinuria, renal failure, hypoglycemia, hypotonia, hepatomegaly, hepatic coma, CHF, neurologic changes–progressive myasthenia, encephalopathy, lethargy, coma, death, cardiomegaly, cardiac arrest, impaired growth and development Want to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit the webmaster's page for free fun content. |
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