cardiotoxin

car·di·o·tox·in

(kar'dē-ō-tok'sin),
1. A poisonous glycoside with specific cardiac effects. For example, causes irreversible depolarization of cell membranes.
2. Specifically, one of the toxic principles from cobra venom.
3. Any substance that can cause heart damage with toxic doses.
References in periodicals archive ?
Concomitant inactivation of the epidermal growth factor receptor, phosphatidylinositol 3-kinase/Akt and Janus tyrosine kinase 2/signal transducer and activator of transcription 3 signalling pathways in cardiotoxin Ill-treated A549 cells.
Mice were randomly divided into two groups: (1) cardiotoxin (CTX)-injected (CX, n = 15) and (2) CTX-injected with MENS treatment (MX, n = 15) groups.
Effects of a cardiotoxin from Naja naja kaouthia venom on skeletal muscle: involvement of calcium-induced calcium release sodium ion currents and phospholipases A2 and C.
Haemolysis: Studies have demonstrated that the venom from cobra has significant hemolytic activity, including a synergistic effect of the cardiotoxin with phospholipidase A2.
Inhibition of Src activation with cardiotoxin III blocks migration and invasion of MDA-MB-231 cells.
Key Words: Magnesium sulphate, Wheat pill, Aluminum phosphide, Phosphine, Cardiotoxin
In general snake venom possesses toxin like neurotoxin, cytotoxic, cardiotoxin, haemolysin and coagulation factors.
Aluminium phosphide poisoning in a young adult: A suicidal cardiotoxin simulating myocardial ischaemia.
Mechanisms of cardiotoxin III-induced apoptosis in human colorectal cancer colo205 cells.

Full browser ?